polycystic


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polycystic

 [pol″e-sis´tik]
containing many cysts.
polycystic kidney disease either of two unrelated hereditary diseases in which there is massive enlargement of the kidney with cyst formation. It occurs in two forms, distinguished by age of onset and other characteristics.

Autosomal dominant polycystic kidney disease (ADPKD, formerly called adult polycystic kidney disease) is the most common type of cystic disease of the kidneys. It is usually manifested during the third decade of life. Renal failure may appear by the fifth decade, with terminal failure occurring in the next ten years, although in some cases it never appears. Although there is rarely any liver dysfunction accompanying this disorder, cyst formation in the liver does occur.

Autosomal recessive polycystic kidney disease (ARPKD), formerly called childhood polycystic kidney disease, is diagnosed at birth or in the first ten years of life and is much less common than the autosomal dominant form. Both the kidney and the liver are involved, causing renal failure and liver failure with portal hypertension. Characteristic symptoms early in the process include pain, hematuria, urinary tract infection, kidney stones, and obstructive uropathy with anuria.

Treatment of both types of polycystic kidney disease is largely symptomatic. Renal dialysis and kidney transplantation during end-stage renal disease can prolong life but offer no cure. Families with histories of polycystic kidney disease require genetic counseling and may need help in coping with the prospect of future offspring afflicted with the disease.
polycystic ovary syndrome (PCOS) a clinical symptom complex associated with polycystic ovaries and characterized by oligomenorrhea or amenorrhea, anovulation (hence infertility), and hirsutism. Both hyperestrogenism (from peripheral conversion of androgen) and hyperandrogenism are present. Excretion of follicle-stimulating hormone and 17-ketosteroids is normal, but infertility is usually persistent, requiring treatment with wedge resection, clomiphene, or gonadotropins. Called also Stein-Leventhal syndrome.
polycystic renal disease polycystic kidney disease.

pol·y·cys·tic

(pol'ē-sis'tik),
Composed of many cysts.

polycystic

/poly·cys·tic/ (-sis´tik) containing many cysts.

polycystic

(pŏl′ē-sĭs′tĭk)
adj.
Having or containing many cysts: polycystic kidney disease.

polycystic

[-sis′tik]
Etymology: Gk, polys + kystis, bag
characterized by the presence of many cysts.

pol·y·cys·tic

(pol'ē-sis'tik)
Composed of many cysts.

polycystic

containing many cysts.

polycystic kidney disease
see polycystic kidney disease.
polycystic liver
congenital anomaly in which cystic remnants of the bile duct occur in the liver; the bile duct is patent; seen in kittens, pups, piglets.
polycystic ovarian disease
multiple thin-walled cysts in one or both ovaries of the mature bitch; may cause hyperestrogenism.
polycystic pancreas
cystic pancreatic and bile ducts and polycystic kidneys may occur in the same patient.
polycystic renal disease
see polycystic kidney disease.
References in periodicals archive ?
Taken together, these papers are examples of how medical scientists are making progress toward developing effective, personalized therapies for polycystic kidney disease and other kidney disorders.
Oxidative stress (OS) plays an important role in the pathophysiology of polycystic ovarian syndrome (PCOS).
Table-2: Biochemical data at baseline and at 3-and 12-week supervised aerobic training follow-ups of obese women with or without polycystic ovary syndrome (PCOS).
The objective of the study is to see the protective effect of Nigella sativa in Letrozole induced polycystic ovarian syndrome.
The report provides comprehensive information on the therapeutics under development for Polycystic Kidney Disease, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type.
Eligibility criteria were age 15-40 years; married; and following Rotterdam criteria: (1) visualization of polycystic ovaries on ultrasound scan, (2) clinical signs of hyperandrogenism, and (3) >35 days interval between menstrual periods and/or amenorrhea defined as absence of vaginal bleeding for at least 6 months.
Winters, "Bone mineral density, androgens, and the polycystic ovary: the complex and controversial issue of androgenic influence in female bone," Journal of Clinical Endocrinology & Metabolism, vol.
Prevalence of cardiovascular events in patients with autosomal dominant polycystic kidney disease.
To determine presence of polycystic ovarian syndrome in adolescent with menstrual disorder.

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