polybasic


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polybasic

 [pol″e-ba´sik]
having several replaceable hydrogen atoms.

pol·y·ba·sic

(pol'ē-bā'sik),
Having more than one replaceable hydrogen atom, denoting an acid with a basicity greater than 1.

polybasic

/poly·ba·sic/ (-ba´sik) having several replaceable hydrogen atoms.

pol·y·ba·sic

(pol'ē-bā'sik)
Having more than one replaceable hydrogen atom; denoting an acid with a basicity greater than 1.

polybasic

having several replaceable hydrogen atoms.
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References in periodicals archive ?
Compound 48/80 and other polybasic compounds are shown to activate G proteins (20,21).
pH calculations involving hydrolysis, polybasic acids, buffer solutions and the common titrametric methods are treated in chapters 7 through 12 with most of the templates providing for graphing.
The HA cleavage site showed polybasic properties RNSPLRERRRKR*GLFGAIA, confirming the high pathogenicity of the virus.
Highly Pathogenic Influenza strains of all clades possess the polybasic cleavage site.
This process showed the polybasic cleavage site PLRERRRKR/ GLF from multiple bird swab and tissue samples from each shed.
It is comprised of applying an organic acid to a substrate to form a layer and drying the layer, wherein the organic acid has at least two acid groups and is selected from the group consisting of a graft polymer, a polybasic carboxylic acid, a polymer of an unsaturated carboxylic acid and a co-polymer of an unsaturated carboxylic acid.
The amino acid sequence of the HA1/HA2-connecting peptide of HA is a major determinant of pathogenicity in terrestrial poultry, and the pathogenicity of highly pathogenic subtype H5N1 and H7N3 viruses is influenced by the presence of a polybasic cleavage site in the connecting peptide (32).
The virus's hemagglutinin (HA) cleavage site had the polybasic amino acid sequence PQRERRRKRGLF, which is characteristic of HPAIVs (22).
9 * PB, polybasic protein; 008, A/duck/eastern China/008/2008(H5N5); 108, A/duck/eastern China/108/2008(H5N1); 031, A/duck/eastern China/031/2009(H5N5); 909, A/duck/eastern China/909/2009(H5N1); 013, A/duck/Yangzhou/013/2008(H6N5); PA, polymerase acidic protein; HA, hemagglutinin; NP, nucelocapsid protein; NA, neuraminidase; M, matrix protein; NS, nonstructural protein.