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pol gene

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pol gene,
a segment of a retrovirus, such as the human immunodeficiency virus, that encodes its reverse transcriptase enzyme.

pol gene
a gene which encodes reverse transcriptase, found in the retroviral genome.


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Since the pol gene ORF partially overlaps the S gene, the Gly/Arg 145 mutation in the S gene sequence corresponds to a Trp/Gln 153 mutation in the pol gene sequence, which results in the expression of an altered polymerase gene product.
The gag and pol genes are considered to be potentially effective components of a vaccine against multiple HIV-1 mutants.
HIV-1 Genotyping In cases in which viral load was >1,000 RNA copies/mL plasma, HIV-1 genotyping was performed by using a protocol (Virco BVBA, Mechelen, Belgium) based on sequencing of a 1,497-bp fragment of the HIV-1 pol gene (position 2253-3749).
 
 
 
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