ploidy analysis

ploidy analysis

A flow cytometry technique which evaluates a cell’s chromosome content—a parameter of aggressiveness in cancer. In general, diploidy (i.e., the presence of 2 haploid sets of chromosomes) is a normal or near-normal state; in contrast, anaplastic and aggressive tumours are more often aneuploid or hyperdiploid. Ploidy analysis is used to prognosticate malignancies in bone (osteosarcoma), as well as in bladder, breast, colon, endometrial and ovarian carcinomas, and lymphoma.

ploidy analysis

Lab medicine A flow cytometry technique that evaluates a cell's chromosome content–a parameter of aggressiveness in CA; in general, diploidy–ie, the presence of 2 haploid sets of chromosomes, is a normal or near-normal state; in contrast, anaplastic and aggressive tumors are more often aneuploid or hyperdiploid; PA is used to prognosticate CA of bone–osteosarcoma, bladder, breast, colon, endometrium, lymphoma, ovary. See Flow cytometry, S-phase analysis.
References in periodicals archive ?
Early investigation in image analysis involved ploidy analysis, which at the time was believed to have a major role in patient stratification to treatment protocols.
disorders CD4, CD8 count Antiglobin test, Platelet function disorder, ploidy analysis
Combination of immunohistochemistry and ploidy analysis to assist histopathological diagnosis of molar diseases.
Extraskeletal myxoid chondrosarcoma: A clinicopathologic, immunohistochemical, and ploidy analysis of 23 cases.
Nuclear DNA, chloroplast DNA, and ploidy analysis clarified biological complexity of the Vandenboschia radicans complex (Hymenophyllaceae) in Japan and adjacent areas.
Refining the diagnosis of hydatidiform mole:image ploidy analysis and P57kip2 Immunohistochemistry.
Combining the results of ploidy analysis and insemination sperm concentration optimization, 75 sec UV irradiation of 1,075 [micro]W [cm.
Current instruments have been used to automate the microscopic urinalysis and histologic or cytologic slides for, as an example, DNA ploidy analysis.
Atypical fibroxanthoma: DNA ploidy analysis of 14 cases with possible histogenetic implications.