plexiform schwannoma

plexiform schwannoma

An uncommon schwannoma (4% of all schwannomas) which arises in superficial soft tissues, most often of the head and neck with a broad age range.

Clinical findings
Can be very large and cause pain, disfigurement, and neurologic and other deficits.

Location
Extremities, retroperitoneum/pelvis, trunk, parotid, vulva, thoracic oesophagus.

Prognosis
Local recurrence, 50%.

Worrisome histologic features
Increased cellularity, 68%; pleomorphism, 50%.

Plexiform schwannoma variants
• Superficial plexiform schwannoma.
• Extensive plexiform schwannoma.
• Deep plexiform schwannoma.
References in periodicals archive ?
Plexiform schwannoma has been rarely reported in association with NF2.