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plexiform neurofibroma

   Also found in: Wikipedia 0.01 sec.
plexiform neurofibroma
n.
A neurofibroma in which Schwann cells proliferate inside the nerve sheath, producing an irregularly thickened, distorted, tortuous structure. Also called plexiform neuroma.


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Patients with NF1 have an increased risk of developing tumors of the central and peripheral nervous system including plexiform neurofibromas (27%), optic gliomas (15-20%), pheochromocytomas (1%), malignant peripheral nerve sheath tumors (5%), and neurofibrosarcomas (6%).
Plexiform neurofibroma, type I Plexiform neurofibroma tumors are often seen in the subcutaneous tissue and extend without respect for fascial planes into multiple compartments.
Malignant schwannoma of the sympathetic chain, combined with plexiform neurofibromas of the tongue and larynx in a patient with von Recklinghausen's disease.
 
 
 
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