pleomorphic xanthoastrocytoma

ple·o·mor·phic xan·tho·as·tro·cy·to·ma

a rare variant of astrocytoma usually presenting early in life with seizures. The tumor is superficially located and composed of pleomorphic glial cells, lipidized astrocytes, and perivascular lymphocytes.
Synonym(s): xanthoastrocytoma

pleomorphic xanthoastrocytoma

(zan″thō-as″trŏ-sī-tō′mă) [ xantho- + astrocytoma],


A rare, relatively slow-growing astrocytoma composed of cells of many sizes and shapes. The tumor is usually diagnosed in adolescents and young adults. Microscopic specimens often reveal fatty cells, fibrillar cells, and involvement of the leptomeninges of the brain.
References in periodicals archive ?
A magnetic resonance imaging scan was subsequently done, and the report suggested the presence of a large, left frontal lobe, multicystic inhomogenous tumour with characteristics consistent with a ganglioglioma or pleomorphic xanthoastrocytoma.
Pleomorphic xanthoastrocytoma (PXA) is rare primary neoplasm of brain.
Keywords: Pleomorphic xanthoastrocytoma, Mural nodule, Supratentorial, GFAP.
Tumor histology of pediatric patients with brain tumors (n=136) Tumor N Pilocytic astrocytoma (WHO grade I) 42 Medulloblastoma 12 Ependymoma (WHO grades I , II, III) 11 Astrocytoma (WHO grade II) 11 Craniopharyngioma 11 Astrocytoma (WHO (grades III & IV) 6 Choroid plexus papilloma (WHO grade I) 5 Germinoma 5 PNET 5 Dermoid cyst 4 SEGA (WHO grade I) 4 Meningioma 3 Ganglioglioma (WHO grade I) 2 Metastatic 2 Oligodendroglioma (WHO grade II) 3 Choroid plexus carcinoma (WHO grade III) 1 Epidermoid cyst 1 Hemangiopericytoma 1 Pilomyxoid astrocytoma 1 Pineocytoma (WHO grade II) 1 Pleomorphic xanthoastrocytoma 2 Rathke's cleft cyst 1 Schwannoma (WHO grade I) 1 Pituitary adenoma 1 Table 3.
Pleomorphic Xanthoastrocytoma (PXA) is a rare tumor in children and young adults.
Pleomorphic xanthoastrocytoma - a clinico-pathological review.
We present a case of melanotic pleomorphic xanthoastrocytoma and discuss its histogenesis.
The tumor was diagnosed as a pigmented (melaninproducing) pleomorphic xanthoastrocytoma.
The pleomorphic xanthoastrocytoma (PXA), described for the first time in 1979, is a rare tumor of the Central Nervous System, accounting for less than 1% of all astrocytic tumors (1,2).
Pleomorphic xanthoastrocytoma (PXA) and ganglioglioma (GG) are typically superficial, supratentorial, solid, and cystic lesions with a predilection for the temporal lobes of young patients who present with a protracted history of seizures.
This edition adds 19 new chapters on topics like recent advances in cytogenetics and molecular biology, inheritable genetic variations predisposing to tumors, surgical strategies and intraoperative imaging, convection therapy, and gangliogliomas, dysembryoplastic neuroepithelial tumors, pleomorphic xanthoastrocytomas, atypical teratoid/rabdoid tumors, and chordomas/skull base tumors.