plasma protein


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plasma protein

albumin, fibrinogen, prothrombin, and the gamma globulins, which constitute 6% to 7% of the blood plasma. Proteins maintain osmotic pressure, increase blood viscosity, and help maintain blood pressure. All the plasma proteins except the gamma globulins are synthesized in the liver. See also antibody, serum.

plasma protein

A protein present in blood plasma, such as albumin or globulin.
See also: protein

plasma

the fluid portion of the blood in which corpuscles are suspended. Plasma is to be distinguished from serum, which is plasma from which the fibrinogen has been separated in the process of clotting.

plasma bound
many electrolytes exist in plasma in a form in which they are bound to protein which reduces their lability and liability to loss in the urine, e.g. protein-bound iodine.
plasma cell gingitivitis-pharyngitis
see feline plasma cell gingivitis-pharyngitis.
plasma cell myeloma
see multiple myeloma.
plasma cell pododermatitis
a nonpainful swelling with ulceration and exuberant granulation tissue on the footpads of cats. The cause is unknown but believed to be immunological.
Enlarge picture
Plasma cell pododermatitis in a cat.
plasma clearing factor
a lipoprotein lipase which lipolyses the triglyceride in the chylomicrons of the plasma and hence clears it of cloudiness.
plasma exchange
the removal of plasma from withdrawn blood (plasmapheresis) and retransfusion of the formed elements and type-specific fresh-frozen plasma into the donor; done for removal of circulating antibodies or abnormal plasma components.
plasma expanders
see plasma volume expander.
fresh-frozen plasma
prepared from whole blood; a source of coagulation factors.
plasma protein
the heterologous group of proteins in circulating blood that includes albumin, lipoproteins, glycoproteins, transcortin, haptoglobin, ceruloplasmin, cholinesterase, α2-macroglobulin, erythropoietin, transferrin, hemopexin, fibrinogen, plasminogen and the immunoglobulins (γ-globulins).
plasma protein:fibrinogen (PP:F) ratio
an indicator of significant changes in fibrinogen levels, taking into account dehydration.
plasma substitute
a fluid suitable for use as a replacement for plasma in the animal body. Usually a solution of gelatin or dextran.
therapeutic plasma concentration
a therapy-response relationship determined only by experiment; the plasma level which is matched by the desired therapeutic response.
plasma thromboplastin antecedent
clotting factor XI; see plasma thromboplastin antecedent.
plasma turbidity test
a qualitative test for fat absorption, performed by comparing the turbidity of plasma before and 2, 3 and 4 hours after the oral administration of fats, usually vegetable oil. Results are greatly influenced by delays in gastric emptying, so normally this test can only be relied upon to rule out malabsorption or maldigestion when evidence of absorption is found.
plasma volume
the estimation of plasma volume is essential to a complete knowledge of a patient's fluid status. The common technique is by the intravenous injection of a known amount of a dye such as Evans blue and the subsequent measurement of the dilution that it has undergone in a set time period.
References in periodicals archive ?
Most plasma proteins are synthesized in the liver and, therefore, low levels may indicate a fiver disorder.
These samples were analyzed to estimate concentrations of carbonyl groups on plasma proteins (CP) and the redox state of human serum albumin (HSA).
Evaluation of pregnancy-associated plasma protein A as a prognostic indicator in acute coronary syndrome patients.
Identifying this repertoire of plasma proteins could offer new ways to detect--or even treat and prevent--many diseases.
Aventis Behring is a global leader in the development and marketing of plasma protein therapies and recombinant products.
introduction to blood components and blood plasma proteins
size or scope of the order: Delivery of reagent kits for the determination of glycated hemoglobin by high performance liquid chromatography with the lease of the analyzer and reagents and accessories: electrophoresis, immunofixation and izoelektroogniskowania plasma proteins and other body fluids, including the lease of analyzers to perform these studies.
Coverage begins with blood components and blood plasma proteins, followed by discussion of domains, motifs and repeats; protein families; and posttranslational modifications.
Gas-phase cigarette smoke (filtered to remove particulate matter) oxidized both plasma proteins and lipids, but whole cigarette smoke oxidized only the proteins.
Released from plasma proteins activated by enzymes, kinins in the blood cause expansion of blood vessels, which allows fluid to leak into surrounding tissue.
In addition, GTC established a strategic collaboration with LFB Biotechnologies of France to jointly develop recombinant forms of human plasma proteins and monoclonal antibodies.