ATP2B3

(redirected from plasma membrane calcium-transporting ATPase 3)

ATP2B3

A gene on chromosome Xq28 that encodes a magnesium-dependent P-type ion transport ATPase, which forms an aspartyl phosphate intermediate during the reaction cycle. P-type primary ion transport ATPases remove bivalent calcium ions from eukaryotic cells against very large concentration gradients, and play a key role in intracellular calcium homeostasis.
References in periodicals archive ?
ATP284 plasma membrane calcium-transporting ATPase 4 (1028 aa) ATP2B1 plasma membrane calcium-transporting ATPase 1 (1220 aa) ATP2B2 plasma membrane calcium-transporting ATPase 2 (1198 aa) A7P2B3 plasma membrane calcium-transporting ATPase 3 (1206 aa) CNBP Cellular nucleic acid-binding protein; Single stranded DNA -binding protein, with specificity to the sterol regulato.
This work then led to the discovery of various plasma membrane channel mutations [sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1), plasma membrane calcium-transporting ATPase 3 (ATP2B3), and voltage-dependent calcium channel type L alpha 1D subunit (CACNA1D)] in other APAs.
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