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pituitary dwarf |
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dwarf (dworf) an abnormally short person.dwarf´ish achondroplastic dwarf one with achondroplasia and a large head with saddle nose and brachycephaly, short limbs, and usually lordosis. Amsterdam dwarf one with de Lange's syndrome. ateliotic dwarf one with infantile skeleton, with persistent nonunion between epiphyses and diaphyses. hypophysial dwarf pituitary d. Laron dwarf one whose skeletal growth retardation is from impaired ability to synthesize insulin-like growth factor I, usually due to growth hormone receptor defects. normal dwarf , physiologic dwarf a person who is unusually short but not deformed. pituitary dwarf a dwarf with hypophysial infantilism. rachitic dwarf a person dwarfed by rickets, having a high forehead with prominent bosses, bent long bones, and Harrison's groove. renal dwarf one whose failure to achieve normal bone maturation is due to renal failure. true dwarf normal d. pituitary dwarf Etymology: L, pituita, phlegm; AS, dweorge a dwarf whose retarded development is caused by a deficiency of growth hormone resulting from hypofunction of the anterior lobe of the pituitary. In most cases the cause is unknown and the defect is limited to a lack of somatotropin, although in some instances gonadotropins, adrenocorticotropic hormone, and thyroid stimulating hormone also may be deficient. The body is properly proportioned, with no facial or skeletal deformities, and mental and sexual development is normal. The condition is usually diagnosed in childhood by radiographic examination of the bones and radioimmunoassay of levels of plasma growth hormone. Also called hypophyseal dwarf, Lévi-Lorain dwarf, Paltauf's dwarf. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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