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pituitary apoplexy

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pituitary apoplexy
Acute life-threatening hemorrhagic infarction of the anterior pituitary or adenohypophysis, often associated with an infarcted pituitary adenoma or other tumor; PA may occur spontaneously, or due to an 'obstetric' hemorrhage–eg, Sheehan syndrome, regional RT, ↑ intracranial pressure, or systemic anticoagulation Clinical The PA 'syndrome' may be transient or permanent; it is characterized by sudden headache, loss of vision, ophthalmoplegia, and if severe, shock Lab ↓ Growth hormone, ↓ gonadotropins, ↓ ACTH, ↓ TSH–with hypothyroidism, abnormal prolactin secretion, rarely, diabetes insipidus Treatment Hormone replacement, bromocriptine


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In pituitary apoplexy syndrome (Figure 4), patients present with ophthalmoplegia, headache, and visual loss due to pituitary infarction/hemorrhage.
London, United Kingdom, Her Majesty's Stationery Office, 1990 Pituitary Apoplexy After Administration of Heparin and Isosorbide Dinitrate To the Editor.
1,10,13) This form of "autoparathyroidectomy" or "parathyroid apoplexy" results in hemorrhagic necrosis of the gland that is similar to processes seen in other endocrine gland neoplasms, namely pituitary apoplexy and adrenal adenoma.
 
 
 
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