piperazine

piperazine /pi·per·a·zine/ (-zen) an anthelmintic used against Ascaris lumbricoides and Enterobius vermicularis; used as the citrate salt.

---

pi·per·a·zine (p-pr-zn, p-)

n.

A colorless crystalline compound used as a hardener for epoxy resins, an antihistamine, and an anthelmintic.

---

piperazine (piper´zēn),

n an anthelmintic agent that acts against the roundworm
Ascaris lumbricoides and the pinworm
Enterobius vermicularis by interfering with their nerve transmissions, thereby causing paralysis.

---

piperazine

an anthelmintic; several of its salts are used, especially in horses and dogs. A useful agent especially against ascarids. Combined with a benzimidazole is effective against Parascaris equorum and benzimidazole-resistant small strongyles.

Piperazine is a very safe medicament but poisoning occurs on doses that are several times normal. Signs include incoordination, pupillary dilatation, hyperesthesia, somnolence, tremor, swaying at rest and recumbency. Spontaneous recovery usual.