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pioglitazone

   Also found in: Wikipedia 0.01 sec.
pioglitazone /pi·o·glit·a·zone/ (pi″o-glit´ah-zōn) an antidiabetic agent that decreases insulin resistance in the peripheral tissues and liver; used as the hydrochloride salt in the treatment of type 2 diabetes mellitus.
pioglitazone,
an oral antidiabetic.
indication It is used to treat stable type 2 diabetes mellitus.
contraindications Lactation, diabetic ketoacidosis, and known hypersensitivity to this drug prohibit its use. It is also contraindicated in children.
adverse effects Common adverse effects include myalgia, sinusitis, upper respiratory infection, pharyngitis, headache, and aggravated diabetes mellitus.

pioglitazone [pi″o-glit´ah-zōn]
an agent used in treatment of type 2 diabetes mellitis, decreasing insulin resistance in the peripheral tissues and liver, used orally as the hydrochloride salt.

pioglitazone
Actos® Endocrinology An oral antidiabetic that ↓ insulin resistance, used to manage type 2 DM; it inhibits hepatic gluconeogenesis, and improves glycemic control while ↓ circulating insulin Adverse effects Edema, ↑ URIs, headaches, myalgias, sinusitis. See Diabetes mellitus.


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Other oral agents can reduce insulin resistance (metformin, pioglitazone, and rosiglitazone) or slow the absorption of sugars from the intestine (acarbose and miglitol).
Among older patients with diabetes, pioglitazone is associated with a significantly lower risk of heart failure and death than is rosiglitazone," they wrote.
With the help of prescription records, boffins identified nearly 40,000 patients aged 66 years and older who started treatment with either rosiglitazone or pioglitazone between April 2002 and March 2008.
 
 
 
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