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pinocytosis
(redirected from pinocytotic)

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.01 sec.
pinocytosis /pino·cy·to·sis/ (pi″nah-si-to´sis) a mechanism by which cells ingest extracellular fluid and its contents; it involves the formation of invaginations by the cell membrane, which close and break off to form fluid-filled vacuoles in the cytoplasm.pinocytot´ic
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Pinocytosis of small fluid droplets.

pin·o·cy·to·sis (pn-s-tss, -s-, pn-)
n.
Introduction of fluids into a cell by invagination of the cell membrane, followed by formation of vesicles within the cells.

pino·cy·totic (-ttk) adj.

pinocytosis
[pī′nōsītō′sis]
Etymology: Gk, pinein + kytos + osis, condition
the process by which extracellular fluid is taken into a cell. The plasma membrane develops a saccular indentation filled with extracellular fluid and then pinches off the indentation, forming a vesicle or vacuole of fluid within the cell.

pinocytosis [pin″o-si-to´sis]
a mechanism by which cells ingest extracellular fluid and its contents; it involves the formation of invaginations by the cell membrane, which close and break off to form fluid-filled vacuoles in the cytoplasm (see accompanying illustration). adj., adj pinocytot´ic.
Mechanism of pinocytosis. Tiny droplets of fluid are trapped by the folds of the plasma membrane and engulfed as fluid-filled vesicles into the cytoplasm.

pinocytosis (pī´nōsītō´sis),
pinocytosis
a mechanism by which cells ingest extracellular fluid and its contents; it involves the formation of invaginations by the cell membrane, which close and break off to form fluid-filled vacuoles in the cytoplasm.
Enlarge picture
Mechanism of pinocytosis. By permission from Guyton R, Hall JE, Textbook of Medical Physiology, Saunders, 2000


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Examination of tumor cells on electron microscopy will reveal (1) desmosomes, (2) arrays of cytoplasmic, uniformly dispersed microfilaments in the presence or absence of dense bodies, and (3) pinocytotic vesicles with basal lamina separating the tumor cells from the stroma.
The exact mechanism behind closure has yet to be elucidated, but it has been proposed that it reflects a combination of exhaustion of pinocytotic capability and enterocyte replacement by a more mature population of gut epithelial cells (Broughton and Lecce, 1970).
However, there may be some subtle differences at the ultrastructural level (eg, meningioma lacks pinocytotic vesicles).
 
 
 
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