pilocarpine /pi·lo·car·pine/ (pi″lo-kahr´pēn) a cholinergic alkaloid, used as the base or the hydrochloride or nitrate salt as an antiglaucoma agent and miotic and as the hydrochloride salt in the treatment of xerostomia associated with radiotherapy or Sjögren's syndrome.
pilocarpine [pi″lo-kahr´pin]
pilocarpine (pi″lokahr´pēn),
pilocarpine
pi·lo·car·pine (p  l -kär p n)n. A colorless or yellow poisonous compound used to induce sweating, promote salivation, and treat glaucoma. |
pilocarpine [pi″lo-kahr´pin]
a cholinergic alkaloid from leaves of Pilocarpus jaborandi and P. microphyllus; used topically in the eye as the base or the hydrochloride or nitrate salt as an antiglaucoma agent and miotic; the hydrochloride salt is also used orally to treat mouth dryness resulting from radiotherapy or associated with Sjögren's syndrome. The nitrate salt has also been administered by iontophoresis to produce sweating in a test for cystic fibrosis.
pilocarpine (pi″lokahr´pēn),
n an alkaloid that causes parasympathetic effects (e.g., secretion of salivary, bronchial, and gastrointestinal glands). It stimulates the sweat glands and also causes vasodilation and cardiac inhibition.
pilocarpine
a cholinergic alkaloid from leaves of Pilocarpus jaborandi and P. microphyllus; used as an ophthalmic miotic in the form of its hydrochloride and nitrate salts.
pilocarpine
An alkaloid obtained from the leaves of Pilocarpus microphyllus and other species of Pilocarpus. It is a parasympathomimetic (direct-acting cholinergic) drug, which mimics the effect of acetylcholine causing miosis and accommodation. It counteracts sympathomimetic mydriatics. It is used in the treatment of glaucoma. Pilocarpine hydrochloride is most commonly applied to the eye as a 1% solution. Carbachol and bethanechol chloride are other parasympathomimetic drugs with similar effects to pilocarpine. See parasympathomimetic drug; physostigmine.
pilocarpine
Therapeutics An alkaloid with mild β-adrenergic activity which, topically, ↓ intraocular pressure in glaucoma; it stimulates glands, resulting in diaphoresis, salivation, lacrimation it may be used to treat
post-radiation or opioid-induced xerostomia, gastric and pancreatic secretion
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