Ticku, "Interactions of pentamethylenetetrazole and tetrazole analogues with the picrotoxinin
site of the benzodiazepine-GABA receptor-ionophore complex," European Journal of Pharmacology, vol.
Ligands for the binding sites of GABA, benzodiazepines, bariburates, picrotoxinin
and loreclezole did not affect the binding of valerenic acid.
Ethanol alleviates suppression in this situation, but isopropyl-bicyclophosphate, a drug that binds to the picrotoxinin
site of the GABA receptor complex, reversed the effects of ethanol on punished responding in a dose-dependent manner.