picornavirus


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Related to picornavirus: orthomyxovirus, reovirus, togavirus, Picornaviridae

picornavirus

 [pi-kor´nah-vi″rus]
any member of a family of extremely small, ether-resistant RNA viruses, including the enteroviruses and rhinoviruses.

pi·cor·na·vi·rus

(pī-kōr'nă-vī'rŭs),
A virus of the family Picornaviridae.

picornavirus

/pi·cor·na·vi·rus/ (pi-kor″nah-vi´rus) an extremely small, ether-resistant RNA virus, one of the group comprising the enteroviruses and the rhinoviruses.

picornavirus

(pē-kôr′nə-vī′rəs, pĭ-)
n. pl. picornavi·ruses
Any of a group of very small viruses, including the enteroviruses and the rhinoviruses, that infect animals and consist of RNA surrounded by an icosahedral protein shell.

picornavirus

[pīkôr′nəvī′rəs]
Etymology: It, pico, small; RNA, ribonucleic acid; L, virus, poison
a member of a group of small ribonucleic acid (RNA) viruses that are ether-resistant. The two main genera are Enterovirus and Rhinovirus. These viruses cause poliomyelitis, herpangina, aseptic meningitis, encephalomyocarditis, and foot-and-mouth disease.

pi·cor·na·vi·rus

(pi-kōr'nă-vī'rŭs)
A virus of the family Picornaviridae.

picornavirus

A family of small, single-strand RNA viruses that includes the polioviruses, the RHINOVIRUSES, the coxsackie viruses and the enteroviruses. From the Italian piccolo , small, and RNA.

picornavirus

a minute, non-enveloped single RNA strand virus, e.g. polioviruses

picornavirus

a member of the virus family Picornaviridae.
References in periodicals archive ?
The panel agreed that pleconaril, administered at a dose of 400 mg three times a day for 5 days, was shown to be effective in the two studies, although the effect was modest: The time it took for symptoms to resolve was a median of a half day faster among all subjects who received pleconaril and a median of 1 day faster among those on pleconaril who were positive for picornavirus at baseline, using a polymerase chain reaction assay.
In collaboration with these investigators, Rossmann's team crystallized a solution of the drugs mixed with the viruses, catching the compounds in the act of binding to the picornavirus capsids.
Our analysis of virion structure, cell entry, genome replication, and particle assembly will identify molecular details and mechanism of function of critical picornavirus life-cycle intermediates.
ViroPharma also is developing an intranasal formulation pleconaril for the treatment of the common cold, and is considering the development of an oral formulation of pleconaril to treat patients suffering from severe or life-threatening picornavirus infections.
For the patient we report, virus in the nasopharyngeal swab sample was identified as a picornavirus by the xTAG Respiratory Virus Panel and by sequence analysis of the viral protein 1 capsid gene (5).
ViroPharma's most advanced product candidate, PICOVIR (pleconaril), is in clinical development for treatment of picornavirus diseases and is under regulatory review at the FDA.
Used therapeutically, the drug halted development of paralysis in mice that had recently been infected with polio-2 or a paralytic ECHO-9 picornavirus.
Phylogenetic patterns of human respiratory picornavirus species, including the newly identified group C rhinoviruses, during a 1-year surveillance of a hospitalized patient population in Italy.
ViroPharma's most advanced product candidate, Picovir(TM), is in clinical development for the treatment of picornavirus diseases, and is the subject of a new drug application (NDA) that has been accepted for review by the U.
A probable new human picornavirus associated with respiratory diseases.
The patent, titled Antisense Antiviral Agent and Method for Treating ssRNA Viral Infection, includes antisense compounds against RNA viruses from the picornavirus, calicivirus, togavirus and flavivirus families, where the antisense agent has an uncharged morpholino backbone supporting a targeting base sequence complementary to a viral target sequence that spans the translation initiation region of the virus.
Application of a reverse transcription-PCR for identification and differentiation of Aichi virus, a new member of the Picornavirus family associated with gastroenteritis in humans.