physostigmine

physostigmine /phy·so·stig·mine/ (-stig´mēn) a cholinergic alkaloid usually obtained from dried ripe seed of Physostigma venenosum (Calabar bean), used as a topical miotic and to reverse the central nervous system effects of an overdosage of anticholinergic drugs; used in the form of the salicylate and sulfate salts.

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physostigmine (fī´sōstig´mēn),

n a cholinergic actylcholinesterase inhibitor prescribed in the treatment of some forms of glaucoma and to reverse effects of neuromuscular blocking agents.

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physostigmine

an alkaloid usually obtained from the dried ripe seed of Physostigma venenosum; used as a topical miotic in the form of the base and of the salicylate and sulfate salts.

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physostigmine challenge test

a test for the diagnosis of cataplexy; after increasing doses of physostigmine, affected dogs show a dose-related severity of reactions when offered food.

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physostigmine 

A reversible anticholinesterase drug used as a parasympathomimetic which, when used in the eye constricts the pupil. It may be used in solution of 0.25-1% or ointment 0.25-0.50% in the treatment of glaucoma, but because of its side-effects its usage is rare nowadays. It is sometimes combined with pilocarpine. Syn. eserine. See miotics; neostigmine; parasympathomimetic drug.

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physostigmine

A reversible antiacetylcholinesterase, used in Pts with Sx of an anticholinergic crisis Neurology Memory drug Physostigmine may improve working memory by ↑ efficiency and ↓ effort. See Working memory.