phototoxic


Also found in: Dictionary, Wikipedia.
Related to phototoxic: phototoxic dermatitis

phototoxic

 [fo´to-tok″sik]
having a toxic effect triggered by exposure to light.

pho·to·tox·ic

(fō'tō-tok'sik),
Relating to, characterized by, or causing phototoxicity.

phototoxic

/pho·to·tox·ic/ (fo´to-tok″sik) having a toxic effect triggered by exposure to light.

phototoxic

(fō′tō-tŏk′sĭk)
adj.
Rendering the skin susceptible to damage by light. Used of certain medications and cosmetics.

pho′to·tox·ic′i·ty (-tŏk-sĭs′ĭ-tē) n.

phototoxic

[-tok′sik]
Etymology: Gk, phos + toxikon, poison
characterized by a rapidly developing nonimmunological reaction of the skin when it is exposed to a photosensitizing substance and light. Compare photoallergic. See also phototoxic contact dermatitis.

Phototoxic

Causes a harmful skin reaction when exposed to sunlight.
Mentioned in: Aromatherapy

phototoxic

having a toxic effect triggered by exposure to light.
References in periodicals archive ?
Photosensitive skin reactions can be the consequence of topical or systemic use of the drug, where phototoxic or photoallergic reactions can occur as a side effect (8-11).
Psoriasis was commonly seen in sixteen cases, airborne allergic contact dermatitis was noticed in nine cases, two cases each was seen in scabies and lichen planus, one case each was noticed in ichthyosis, phototoxic dermatitis, pityriasis rubra pilaris, pemphigus foliaceus, dermatophytosis respectively, this correlates with study of Pal and Haroon et.
Phototoxic dermatitis (DFS), also known as hepatogenic or secondary photosensitization, is defined as skin sensitivity to sunlight due to the presence of photodynamic agents (1) in severe cases of photosensitive dermatitis.
Additional drugs that can produce phototoxic reactions include amiodarone, psoralens and phenothiazines, anticancer drugs, retinoids, zidovudine, and quinine.
However, other factors such as sex and environmental influences such as smoking cigarettes, heart and vascular disorders, hypertension, dyslipidemia/hypercholesterolemia, diabetes, obesity, improper diet, sedentary lifestyle, and phototoxic exposure are also important [179-181].
Although, berberine is phototoxic [12] but Berberis aristata extract found safe with LD50greater than 5000 mg/kg body weight in mice [13] which is in accordance to this research in which it showed higher LC50.
The uses of these chemical compounds and synthetic coating materials have not practical applications due to the high cost, lack of availability and phototoxic effects (Purkayastha, 2009).
The latter compounds exhibited phototoxic activity in a Lemna minor bioassay (7).
These essential oils are phototoxic and can cause pigmentation changes and skin burns up to 12 hours after application when exposed to the sun.
Recently, bio-pesticides with plant origin are given for use against several insect species, especially disease transmitting vectors, based on the fact that compounds of plant origin are safer to use, without phototoxic properties and leave no scum in the environment (15).