phototoxic


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Related to phototoxic: phototoxic dermatitis

phototoxic

 [fo´to-tok″sik]
having a toxic effect triggered by exposure to light.

pho·to·tox·ic

(fō'tō-tok'sik),
Relating to, characterized by, or causing phototoxicity.

phototoxic

/pho·to·tox·ic/ (fo´to-tok″sik) having a toxic effect triggered by exposure to light.

phototoxic

(fō′tō-tŏk′sĭk)
adj.
Rendering the skin susceptible to damage by light. Used of certain medications and cosmetics.

pho′to·tox·ic′i·ty (-tŏk-sĭs′ĭ-tē) n.

phototoxic

[-tok′sik]
Etymology: Gk, phos + toxikon, poison
characterized by a rapidly developing nonimmunological reaction of the skin when it is exposed to a photosensitizing substance and light. Compare photoallergic. See also phototoxic contact dermatitis.

Phototoxic

Causes a harmful skin reaction when exposed to sunlight.
Mentioned in: Aromatherapy

phototoxic

having a toxic effect triggered by exposure to light.
References in periodicals archive ?
Sunlight-activated insecticides: Historical background and mechanisms of phototoxic activity.
Alpha-terthienyl, a non-photodynamic phototoxic compound.
4) Primary photosensitization is a cutaneous disorder that results from ingestion of phototoxic substances.
Phototoxic burning may occur, although extreme blistering and oedema is more a feature of Gunther's disease--the rarer autosomal recessive form (3).
The carotenoids also appear to protect humans against phototoxic damage.
GOTHENBURG, SWEDEN -- A resorbable subcutaneous implant of afamelanotide significantly reduced painful phototoxic attacks in patients with erythropoietic protoporphyria in a year-long multinational clinical trial.
The present investigation was a preliminary screening for phototoxic activity in natural products with antibacterial activities from medicinal plants used in Brazil.
Results released today from a Phase III trial of the drug SCENESSE (R), conducted by Melbourne-based Clinuvel Pharmaceuticals Limited (ASX:CUV) (PINK:CLVLY), have shown that the drug has the ability to reduce and prevent painful phototoxic reactions experienced by patients with erythropoietic protoporphyria (EPP).
There results exhibited that HepG2 was resistant to the phototoxic effect of these two photosensitizers with concentrations up to 4uM and light dose of 40 J/cm2 (Chi-Fung, et al.
The clinical name for the condition is phytophotodermatitis (PPD), sometimes called phototoxic dermatitis [see inset photo on previous page].
When the light is combined with the drug, phototoxic reactions induce the destruction of bacterial cells.
Other plants, such as giant hogweed Heracleum mantegazzianum and garden rue Ruta graveolens, cause a phototoxic reaction.