photophoresis


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ex·tra·cor·po·re·al pho·to·pho·re·sis

destruction of cells separated from blood in an extracorporeal flow system by ultraviolet activation of chemotherapeutic agents such as psoralens.

photophoresis

(fo-to-for-e'sis)
A technique used in treating cutaneous T-cell lymphoma. It incorporates exposure of a lymphocyte-enriched blood fraction, obtained by use of apheresis to ultraviolet A light after the patient has ingested the cytotoxic agent 8-methoxypsoralen.
Synonym: extracorporeal photochemotherapy
References in periodicals archive ?
9 Therakos - Photophoresis of Peripheral Blood Cells
Patent ductus arteriosus - closure; Patent foramen ovale - closure ; Pectus excavatum and Pectus carinatum - Surgical Correction; Percutaneous radiofrequency ablation for primary and secondary lung cancers; Photophoresis, extracorporeal - Therapy for Heart Transplant Rejection; Post-thoracotomy Pain - Intraoperative, Intercostal Nerves, Cryoanalgesia; Pulmonary vein isolation for a trial fibrillation; Pulmonary valve repair and/or replacement;
Fifteen (15) patients with myelodysplastic syndrome (MDS) received a novel preparative regimen consisting of Nipent, low- dose radiation and photophoresis treatments (where blood is exposed to ultraviolet light) prior to an allogeneic bone marrow transplant (from a donor, rather than from oneself).
Kenneth Miller from the New England Medical Center presented data demonstrating that Nipent is a major component of a novel, less toxic regimen that also includes photophoresis and reduced-dose total body irradiation administered to cancer patients prior to 'allogeneic' (from a donor rather than one's self) bone marrow transplants.
Other available therapies for CTCL, such as electron beam treatment, photophoresis, and Psoralen plus ultraviolet light (PUVA), require frequent visits to a clinic, hospital or doctor's office for administration by a healthcare professional.
Nasdaq: SUPG) announced today that data from a study of its anticancer compound pentostatin (Nipent) shows that it is a major component of a novel, less toxic regimen that also includes photophoresis and reduced-dose total body irradiation administered to cancer patients prior to 'allogeneic' (from a donor rather than one's self) bone marrow transplants.