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phosphorylation |
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phosphorylation /phos·phor·y·la·tion/ (fos-for?i-la´shun) the metabolic process of introducing a phosphate group into an organic molecule. oxidative phosphorylation the formation of high-energy phosphate bonds by phosphorylation of ADP to ATP coupled to the transfer of electrons from reduced coenzymes to molecular oxygen via the electron transport chain; it occurs in the mitochondria. substrate-level phosphorylation the formation of high-energy phosphate bonds by phosphorylation of ADP to ATP (or GDP to GTP) coupled to cleavage of a high-energy metabolic intermediate.
phosphorylation (fos´f n the addition of phosphate to an organic compound. phosphorylation the process of introducing a phosphate group into an organic molecule. oxidative phosphorylation the final common oxidative pathway in which high-energy phosphate bonds are formed by phosphorylation of ADP to ATP by harnessing by F0,F1-ATPase of the proton motive force generated from pumping of protons from the matrix of mitochondria across the inner mitochondrial membrane to the intermembrance space and is coupled with the transfer of electrons along a chain of carrier proteins with molecular oxygen as the final acceptor. |
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