necrosis /ne·cro·sis/ (nĕ-kro´sis) pl. necro´ses [Gr.] the morphological changes indicative of cell death caused by progressive enzymatic degradation; it may affect groups of cells or part of a structure or an organ.
Necrosis
necrosis
necrosis [nĕ-kro´sis, ne-kro´sis] (Gr.)
necrosis (n
·krōˑ·sis),
necrosis (nekrō´sis),
necrosis
Patient discussion about necrosis.
aseptic necrosis necrosis without infection, usually in the head of the femur after traumatic hip dislocation.
Balser's fatty necrosis gangrenous pancreatitis with omental bursitis and disseminated patches of necrosis of fatty tissues.
caseous necrosis cheesy n.
central necrosis that affecting the central portion of an affected bone, cell, or lobule of the liver.
cheesy necrosis that in which the tissue is soft, dry, and cottage cheese–like; most often seen in tuberculosis and syphilis.
coagulation necrosis necrosis of a portion of some organ or tissue, with formation of fibrous infarcts, the protoplasm of the cells becoming fixed and opaque by coagulation of the protein elements, the cellular outline persisting for a long time.
colliquative necrosis that in which the necrotic material becomes softened and liquefied.
contraction band necrosis a cardiac lesion characterized by hypercontracted myofibrils and contraction bands and mitochondrial damage, caused by calcium influx into dying cells resulting in arrest of the cells in the contracted state.
fat necrosis that in which the neutral fats in adipose tissue are split into fatty acids and glycerol, usually affecting the pancreas and peripancreatic fat in acute hemorrhagic pancreatitis.
liquefaction necrosis colliquative n.
phosphorus necrosis necrosis of the jaw bone due to exposure to phosphorus.
postpartum pituitary necrosis necrosis of the pituitary during the postpartum period, often associated with shock and excessive uterine bleeding during delivery, and leading to variable patterns of hypopituitarism.
subcutaneous fat necrosis induration of the subcutaneous fat in newborn and young infants.
necrosis ustilagi´nea dry gangrene due to ergotism.
Zenker's necrosis see under degeneration.
ne·cro·sis (n -kr  s s)n. pl. ne·cro·ses (-s  z ) Death of cells or tissues through injury or disease, especially in a localized area of the body. ne·crot ic (-kr tk) adj. |
Necrosis
The death of cells, a portion of tissue, or a portion of an organ due to permanent damage of some sort, such as a lack of oxygen supply to the tissues.
necrosis
[nekrō′sis]
Etymology: Gk, nekros + osis, condition
localized tissue death that occurs in groups of cells in response to disease or injury. In coagulation necrosis, blood clots block the flow of blood, causing tissue ischemia distal to the clot. In gangrenous necrosis, ischemia combined with bacterial action causes putrefaction to set in. See also gangrene.
necrosis [nĕ-kro´sis, ne-kro´sis] (Gr.)
the morphological changes indicative of cell death caused by enzymatic degradation.
aseptic necrosis necrosis without infection or inflammation.
acute tubular necrosis acute renal failure with mild to severe damage or necrosis of tubule cells, usually secondary to either nephrotoxicity, ischemia after major surgery, trauma (see crush syndrome), severe hypovolemia, sepsis, or burns. See also lower nephron nephrosis.
Balser's fatty necrosis gangrenous pancreatitis with omental bursitis and disseminated patches of necrosis of fatty tissues.
bridging necrosis septa of confluent necrosis bridging adjacent central veins of hepatic lobules and portal triads characteristic of subacute hepatic necrosis.
caseous necrosis caseation (def. 2).
central necrosis necrosis affecting the central portion of an affected bone, cell, or lobule of the liver.
cheesy necrosis caseation (def. 2).
coagulation necrosis death of cells, the protoplasm of the cells becoming fixed and opaque by coagulation of the protein elements, the cellular outline persisting for a long time.
colliquative necrosis liquefactive necrosis.
fat necrosis necrosis in which fat is broken down into fatty acids and glycerol, usually occurring in subcutaneous tissue as a result of trauma.
liquefactive necrosis necrosis in which the necrotic material becomes softened and liquefied.
massive hepatic necrosis massive, usually fatal, necrosis of the liver, a rare complication of viral hepatitis (fulminant hepatitis) that may also result from exposure to hepatotoxins or from drug hypersensitivity.
moist necrosis necrosis in which the dead tissue is wet and soft.
postpartum pituitary necrosis see postpartum pituitary necrosis.
selective myocardial cell necrosis myofibrillar degeneration.
subcutaneous fat necrosis of newborn a benign, self-limited disease affecting term newborns and young infants, characterized by circumscribed, indurated, nodular areas of fat necrosis. It is thought to be related to trauma on bony prominences during delivery, hypothermia, asphyxia, or maternal diabetes; it usually resolves spontaneously by 2 to 4 weeks with no scarring. Called also adiponecrosis neonatorum or subcutanea.
Zenker's necrosis hyaline degeneration and necrosis of striated muscle; called also Zenker's degeneration.
necrosis (n
·krōˑ·sis),n tissue death due to disease or localized injury.
necrosis (nekrō´sis),
n 1. the death of a cell or group of cells in contact with living tissue.
n 2. the local death of cells resulting from, e.g., loss of blood supply, bacterial toxins, or physical or chemical agents.
n 2. the local death of cells resulting from, e.g., loss of blood supply, bacterial toxins, or physical or chemical agents.
necrosis, avascular
n the consequence of temporary or permanent cessation of blood flow to the bones. The absence of blood causes the bone tissue to die, resulting in fracture or collapse of the entire bone.
necrosis, caseous
n a change commonly associated with tuberculosis and characterized by dry, soft, and cheesy tissue.
necrosis, exanthematous
n an acute necrotizing process involving the gingivae, jawbones, and contiguous soft tissues. It is of unknown cause, primarily affects children, and resembles noma. It differs from noma, however, in that it has a slight odor, tendency for self-limitation, low mortality rate, and normal leukocyte count. See also noma.
necrosis, gingival,
n death and degeneration of the cells and other structural elements of the gingivae (e.g., necrotizing ulcerative gingivitis).
necrosis, interdental,
n a progressive disease that destroys the tissue of the papillae and creates interdental craters. Advanced interdental necrosis leads to a loss of periodontal attachment.
necrosis, ischemic,
n death and disintegration of a tissue resulting from interference with its blood supply, thus depriving the tissues of access to substances necessary for metabolic sustenance. It may occur in the periodontal ligament as a result of occlusal trauma.
necrosis of epithelial attachment,
n the death of cells composing the epithelial attachment. In a specific periodontitis produced by organisms similar to
Actinomyces, necrosis of the epithelial attachment may exist, permitting a rapid apical shift of the base of the pocket.
Actinomyces, necrosis of the epithelial attachment may exist, permitting a rapid apical shift of the base of the pocket.
necrosis, periodontal ligament,
n necrosis of a portion of the periodontal ligament, usually resulting from traumatic injury (e.g., in occlusal traumatism). Much of this necrotic change is the result of ischemia.
necrosis, radiation,
n the death of tissue caused by radiation.
necrosis
pl. necroses [Gr.] the morphological changes indicative of cell death caused by enzymatic degradation.
aseptic necrosis
necrosis without infection or inflammation.
caseous necrosis
necrosis in which the tissue is soft, dry and cheesy, occurring typically in tuberculosis.
central necrosis
necrosis affecting the central portion of an affected bone, cell or lobule of the liver.
cheesy necrosis
that in which the tissue resembles cottage cheese; most often seen in tuberculosis.
coagulation necrosis
death of cells, the protoplasm of the cells becoming fixed and opaque by coagulation of the protein elements, the cellular outline persisting for a long time.
colliquative necrosis
see liquefactive necrosis (below).
liquefactive necrosis
necrosis in which the necrotic material becomes softened and liquefied.
moist necrosis
necrosis in which the dead tissue is wet and soft.
Zenker's necrosis
hyaline degeneration and necrosis of striated muscle; called also Zenker's degeneration.
necrosis
Death of some or all cells in an organ or tissue. The process involves swelling of the nucleus (pyknosis), fragmentation of the nucleus (karyorrhexis) and complete dissolution of the nuclear chromatin (karyolysis). Necrosis is caused by disease, trauma or interference with blood supply. There are many sequelae to ocular necrosis (e.g. inflammation, reduction in aqueous humour production following ciliary epithelium necrosis, corneal opacity following necrosis of corneal epithelial cells, and visual loss and floaters following retinal necrosis). See apoptosis; retinal necrosis.
necrosis
Pathology Cell or tissue death due to disease, trauma, hypoxia, radiation, acute infection, etc; the constellation of changes that accompany and follow irreversible cell injury in living organisms. See Acute tubular necrosis, Aseptic necrosis, Bridging necrosis, Coagulation necrosis, Colliquative necrosis, Contraction band necrosis, Cystic medial necrosis, Fat necrosis, Fibrinoid necrosis, Liquefaction necrosis, Lymph node necrosis, Osteonecrosis, Osteoradionecrosis, Papillary necrosis, Piecemeal necrosis, PORN.
Patient discussion about necrosis.
Q. can necrosis in a brain tumor kill you? If so, how? husband has glioblastoma.Tumor seems under control at this point as much as they can tell but sounds like there is a lot of necrosis. He has lots of tumor progression symptoms but since he has had the tumor for so long == 6 years = I guess the necrosis is there moreso than the actual tumor == how dangerous can this be?
A. Tumors and not only in the brain tend to develop necrosis the longer they exist because the tumor cells divide so rapidly so the blood supply can't keep up with its' own cells demands, so some cells within the tumor die (therefore are seen as necrotic). This does not usually predict prognosis, but only means that the tumor is longstanding.
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