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phosphoinositide

   Also found in: Wikipedia 0.01 sec.
phosphoinositide /phos·pho·ino·si·tide/ (-in-o´sĭ-tīd) any of a number of phosphorylated inositol-containing compounds that play roles in cell activation and calcium mobilization in response to hormones.


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2004) The insulin like growth factor 1 receptor induces physiological heart growth via the phosphoinositide 3-kinase (p110alpha) pathway.
The research team led by Eric Howlett discovered an unanticipated connection between glutamate - an amino acid and neurotransmitter in much of the food we eat - and phosphoinositide 3-kinase (PI3K), an enzyme that, Howlett found, regulates the activity of neurons.
This is achieved by inhibition the key enzymes of the phosphoinositide pathway the inositol monophosphatase (IMP) and inositol polyphosphate 1-phosphmonoesterase (7, 9).
 
 
 
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