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phosphodiesterase

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phosphodiesterase /phos·pho·di·es·ter·ase/ (-di-es´ter-ās) any of a group of enzymes that catalyze the hydrolytic cleavage of an ester linkage in a phosphoric acid compound containing two such ester linkages.
phos·pho·di·es·ter·ase (fsf-d-st-rs, -rz)
n.
Any of a class of enzymes that catalyze the cleaving of phosphodiester bonds, such as those between nucleotides in nucleic acids, to produce smaller nucleotide units or mononucleotides but not inorganic phosphate.

phosphodiesterase
a group of enzymes that catalyze the hydrolysis of a phosphodiester.


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However, these medications - which belong to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors - have limitations.
g furosemide, salicylates and phosphodiesterase type 5 inhibitors, e.
These findings are important not only because women experience major depressive disorder at nearly double the rate of men and because they experience greater resulting sexual dysfunction than men, but also because [they established] that selective phosphodiesterase type 5 inhibitors are effective" for reducing adverse sexual effects in women, said Dr.
 
 
 
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