phosphate nephropathy


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Related to phosphate nephropathy: hyperphosphatemia

phosphate nephropathy

Precipitation of phosphate crystals in the renal tubules, e.g., after phosphate-containing laxatives are administered.
See also: nephropathy
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References in periodicals archive ?
Sodium phosphate never should be given to older adults or persons who take angiotensin receptor blockers or angiotension-converting enzyme inhibitors; such persons are predisposed to acute phosphate nephropathy (Heher, Thier, Rennke, & Humphreys, 2008; Khurana, McLean, Atkinson, & Foulks, 2008).
Acute phosphate nephropathy following oral sodium phosphate bowel purgative: an under-recognized cause of chronic renal failure.
Acute phosphate nephropathy presents as acute kidney injury with minimal proteinuria and a bland urine sediment.
Obtain baseline and post-procedure labs (electrolytes, calcium, phosphate, BUN, and creatinine) in patients who may be at increased risk for acute phosphate nephropathy, including those with vomiting and/or signs of dehydration.
Risk factors for phosphate nephropathy in these patients are high basal serum phosphate levels, increased bowel transit time, need for high purgative dosages, increased tubular phosphate re-absorption, advanced age and the concurrent administration of some drugs.
Unfortunately, the outcome of acute phosphate nephropathy following oral sodium phosphate bowel purgatives is poor.