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phocomelia

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phocomelia /pho·co·me·lia/ (fo″kah-me´le-ah) congenital absence of the proximal portion of a limb or limbs, the hands or feet being attached to the trunk by a small, irregularly shaped bone.phocome´lic
pho·co·me·li·a (fk-ml-, -mly)
n.
A birth defect in which the upper portion of a limb is absent or poorly developed, so that the hand or foot attaches to the body by a short, flipperlike stump.

phoco·melic (-mlk) adj.

phocomelia
[fō′kəmē′lyə]
Etymology: Gk, phoke, seal, melos, limb
a developmental anomaly characterized by absence of the upper part of one or more of the limbs so that the feet or hands or both are attached to the trunk of the body by short, irregularly shaped stumps, resembling the fins of a seal. The condition, caused by interference with the embryonic development of the long bones, is rare and is seen primarily as a side effect of the drug thalidomide taken during early pregnancy. Also called seal limbs. Compare amelia. phocomelic, adj.

phocomelia [fo″ko-me´le-ah]
congenital absence of the proximal portion of a limb or limbs, the hands or feet being attached to the trunk by a small, irregularly shaped bone. adj., adj phocome´lic.

phocomelia
congenital absence of the proximal portion of a limb or limbs, the distal parts being attached to the trunk by a small, irregularly shaped bone.

phocomelia
Teratology A congenital malformation characterized by attachment of a hand to the shoulder or foot to the pelvis, imparting a seal flipper appearance, classically associated with exposure of a developing fetus to thalidomide. Cf Thalidomide.


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Vujicic, from Melbourne, enjoys everything other lads his age do - playing football, swimming, and surfing, and while doctors know the condition is caused by a rare occurrence called Phocomelia, not much else is known about why it happened to him.
This report of thalidomide-induced phocomelia was the first published report alerting the medical community to this clinical problem.
This effect is not a mutation and the same can probably be said about phocomelia (e.
 
 
 
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