phenytoin-induced gingival overgrowth


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phenytoin-induced gingival overgrowth

Phenytoin-induced gingival hyperplasia Hyperplasia of gums induced by direct stimulation of gingival fibroblasts, resulting in ↑ collagen synthesis; PIGO is seen in 10-30% of phenytoin-treated Pts. Cf Phenytoin lymphadenopathy.
References in periodicals archive ?
Regression of phenytoin-induced gingival overgrowth after withdrawal of medication.
Development of phenytoin-induced gingival overgrowth in non-institutionalized epileptic children subjected to different plaque control programs.
Studies of patients taking this anticonvulsant drug suggest that bacterial plaque is an important determinant of the severity of phenytoin-induced gingival overgrowth and stress the importance of instituting preventive plaque control programs, principally in young patients taking this drug.