phenylbutazone


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phenylbutazone

 [fen″il-bu´tah-zōn]
a nonsteroidal antiinflammatory drug administered orally in the short-term treatment of severe rheumatoid disorders unresponsive to less toxic agents. It is given for periods of less than one week because it can cause aplastic anemia and agranulocytosis.

phenylbutazone

/phen·yl·bu·ta·zone/ (-bu´tah-zōn) a nonsteroidal antiinflammatory drug used in the short-term treatment of severe rheumatoid disorders unresponsive to less toxic agents.

phenylbutazone

Therapeutics An NSAID tightly bound to plasma proteins. See NSAIDs.

phenylbutazone

A non-steroidal anti-inflammatory drug (NSAID) once widely used but now available for use in hospitals only because of its tendency to cause HEART FAILURE from fluid retention and severe blood disorders. It is used, under specialist supervision, in cases of ANKYLOSING SPONDYLITIS.

phenylbutazone

a powerful anti-inflammatory drug first used in the 1940s in the treatment of arthritis. Limited by its potentially serious side effects (including fatalities), it is now rarely used in humans (ankylosing spondylitis is an exception) but interestingly is used in equestrian sports to treat soft tissue injuries in horses.

phenylbutazone

pyrazole painkiller, used to treat ankylosing spondylitis

phenylbutazone

a nonsteroidal anti-inflammatory drug resembling cortisone in its action; used in the treatment of painful conditions of joints and skeletal muscles. It has powerful analgesic and antipyretic effects, but causes bone marrow suppression with high doses or prolonged administration.
References in periodicals archive ?
Positive Oxyphenbutazone 16 07 Phenylbutazone 08 03 Acetyl salicylic acid 09 -- Analgin 13 01 Sulphadiazine 09 01 Sulphadimethoxine 07 -- Trimethoprim 11 -- Sulphamethoxazole 11 02 Dapsone 08 -- T etracycline 09 -- Oxytetracycline 06 -- Doxycycline 08 -- Paracetamol 02 -- Isonicotinic acid hydrazide 01 -- Thiacetazone 01 01 Procaine penicillin 08 --
Agriculture Minister Stephane Le Foll said that although some of the meat had been recalled, the equivalent of three carcasses had "probably" made it to consumers, but added there was "no health risk" since the traces of phenylbutazone found in the meat were "extremely weak".
Ketoprofen has a wide safety margin and low toxicity compared to phenylbutazone and flunixin meglumine in horses (Mozaffari et al.
She was treated with penicillin twice a day, phenylbutazone, and vitamin B1 over the next 3 days.
Effectiveness of administration of phenylbutazone alone or concurrent administration of phenylbutazone and flunixinmeglumine to alleviate lameness in horses.
The Okapuka Feedlot was placed under quarantine on 1 February after an European Union (EU) inspection team detected Phenylbutazone on the feedlot's medicine register.
Toxicity with phenylbutazone in a horse: a case report *
Common drugs associated with blood dyscrasias Aplasia Agranulocytosis Thrombo- Haemolytic cytopenia anaemia Gold Anti-thyroid Gold Beta-lactams drugs Choramphenicol Phenylbutazone Heparin Quinine/ quinidine Penicillamine Sulphonamide Quinine/ Thiazides quinidine NSAIDs Clozapine Sulphonamides Sulphonamides Sulphonamides Phenothiazines Anticonvulsants NSAIDs Anti-thyroid Mianserin NSAIDs Rifampicin drugs Sulphonylureas NSAIDs Diuretics Isoniazid Phenothiazides Beta-lactams Rifampicin Phenothiazines Allopurinol Captopril Sulphonylureas Sulphonylureas [H.
Hanks balanced salt solution (HBSS), croton oil, arachidonic acid, dextran, carrageenan, zymosan, plate-let-activating factor (PAF), indomethacin, phenylbutazone, methysergide, dexamethasone, phorbol-12-mirystate-13-acetate (PMA), N-formyl-methionyl-leucyl-phenylalanine (FMLP), sodium nitroprusside (SNP), W-13, H-7, genistein and propidium iodide were purchased from Sigma Chemical Co (USA).
Iodine kinetics of the organism under the influence of phenylbutazone.
According to the book Goat Medicine, you may try aspirin (100 mg/kg every 12 hours) or phenylbutazone (10 mg/kg once a day).