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phenolsulfonphthalein

   Also found in: Encyclopedia 0.01 sec.
phe·nol·sul·fon·phthal·ein (fnl-slfn-thln, -thl-n, -thln, -thl-n, -slfn-)
n. Abbr. PSP

phenolsulfonphthalein
[fē′nəlsul′fōnfthal′ē·in]
a bright red water-soluble triphenylmethane dye used as an indicator at pH 7.7. Also called phenol red. See also cystochromoscopy.

phenolsulfonphthalein
an acid-base indicator dye; abbreviated PSP.

phenolsulfonphthalein (PSP) clearance test
after an injection of the dye, urine samples are collected at timed intervals and the amount of excreted dye is determined and plotted against time as an indicator of renal function, particularly renal blood flow, tubular excretion, and to some extent glomerular filtration.


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Liver and kidney function tests requiring the administration of phthalein compounds such as bromsulfophthalein, phenolsulfonphthalein (PSP), or phenyl ketones (large quantities) may interfere with the ketone tests.
Lipophilic impurities, not phenolsulfonphthalein, account for the estrogenic activity in commercial preparations of phenol red.
 
 
 
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