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phenazone

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phenazone /phen·a·zone/ (fen´ah-zōn) antipyrine.
antipyrine [an″te-, an″ti-pi´rēn]
a compound formerly used as an analgesic and antipyretic, now replaced by safer and more effective agents. Its current uses are as a component of multi-ingredient ear drop solutions and complexed with chloral hydrate in dichloralphenazone, a sedative and hypnotic used for headaches. Called also phenazone.

phenazone
an analgesic and antipyretic. Poisoning is characterized by convulsions and collapse. Called also antipyrine.


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Pb effects on liver drug metabolism were reported in early studies, where diminished phenazone elimination rates in men who had been occupationally exposed to Pb and who had evidence of clinical Pb poisoning were reversed after the patients had been treated with EDTA chelation therapy (Fischbein et al.
Arch Int Med 157: 1802-1817 Tinder, P (1969) Determination of blood glucose using 4-amino phenazone as oxygen acceptor.
Under one landfill, Ternes found groundwater tainted with 12 ppb clofibric acid and 1 ppb phenazone, an analgesic.
 
 
 
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