phase III trial


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phase III trial

, phase 3 trial
A clinical trial to explore the clinical use of a new drug, esp. relative to other known effective agents (the current standard of care). These trials often include thousands of enrollee patients. By law, all such patients receive real treatment; no placebos are given. But the trial is usually double-blinded, with patients divided randomly into two groups: an experimental group and a control group on standard treatment, with neither patients nor researchers knowing to which group the patient belongs.
See also: trial
References in periodicals archive ?
The pivotal Phase III trial evaluated the efficacy and safety of a six day course of oral tedizolid phosphate therapy versus 10 days of oral therapy with linezolid (Zyvox) in 667 patients.