phase II detoxification

phase II detoxification,

n the second step in the two-step process for neutralizing toxic chemicals in the liver, during which several enzymes combine with the toxins to convert them into neutral substances or to make them easier to eliminate from the body.
References in periodicals archive ?
A reduced phase II detoxification leads to the accumulation of toxins.
1000] covers phase II detoxification enzymes that include glutathione S-transferse, sulfotransferase 1a1, betainehomocysteine methyltransferase 2, and UDP glucuronosyltransferease 1A1.
Apparently, the protective substances induce a phase II detoxification pathways which minimize and help repair the damages in our DNA caused by our unhealthy and self-destructive lifestyle.
Cysteine plays a role in the sulfation cycle, acting as a sulfur donor in phase II detoxification and as a methyl donor in the conversion of homocysteine to methionine.
The influence of coordinate overexpression of glutathione phase II detoxification gene products on drug resistance.
Seacure, described above, is an important whole-food source of amino acids and an aid to Phase II detoxification.
Silver which has a positive charge is bound up by negatively charged chloride, and is processed through the liver's phase II detoxification pathway and excreted within 24 to 48 hours.
Phase II detoxification metabolism is a potential therapeutic target in toxic exposures.
Wasabia japonica is a potent source of long chain isothiocyanates--natural compounds found in foods such as broccoli and cabbage--that support Phase I and Phase II detoxification in the liver and promote specific immune functions, according to the company.
Glutathione in Phase II detoxification Oxidative stress and carcinogen catabolism Conjugation of reduced glutathione Phase 1 cytochrome P450 metabolism of estrogens and carcinogens