phagocytosis


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phagocytosis

 [fag″o-si-to´sis]
the engulfing of microorganisms or other cells and foreign particles by phagocytes. adj., adj phagocytot´ic.
Phagocytosis. From Damjanov, 2000.

phag·o·cy·to·sis

(fag'ō-sī-tō'sis),
The process of ingestion and digestion by cells of solid substances, for example, other cells, bacteria, bits of necrotic tissue, foreign particles.
See also: endocytosis.
[phagocyte + G. -osis, condition]

phagocytosis

/phago·cy·to·sis/ (-si-to´sis) the engulfing of microorganisms or other cells and foreign particles by phagocytes.phagocytot´ic
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Phagocytosis.

phagocytosis

(făg′ə-sī-tō′sĭs)
n.
The engulfing and ingestion of foreign bodies such as bacteria or other cells by phagocytes or certain protists, such as amoebas.

phag′o·cy·tot′ic (-tŏt′ĭk) adj.

phagocytosis

[fag′əsītō′sis]
Etymology: Gk, phagein + kytos + osis, condition
the process by which certain cells engulf and destroy microorganisms and cellular debris. The process includes five steps: (1) invagination, (2) engulfment, (3) internalization and formation of the phagocyte vacuole, (4) fusing of lysosomes to digest the phagocytosed material, and (5) release of digested microbial products. phagocytize, v.
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Phagocytosis

phag·o·cy·to·sis

(fāg'ō-sī-tō'sis)
The process of ingestion and digestion by cells of solid substances, e.g., other cells, bacteria, bits of necrotic tissue, foreign particles.
See also: endocytosis
[phagocyte + G. -osis, condition]

phagocytosis

(fag?o-si-to'sis) [? + ? + osis, condition]
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PHAGOCYTOSIS
A three-stage process by which phagocytes (neutrophils, monocytes, and macrophages) engulf and destroy microorganisms, other foreign antigens, and cell debris. Generally, these substances must be covered with opsonins, such as antibodies or complement, to initiate binding with cell receptors on the phagocytes, the first stage in phagocytosis. In the second stage, the particle is engulfed and enclosed in a vacuole (phagosome). During the third stage, the phagosome merges with lysosomes whose enzymes destroy the engulfed particle. See: illustration; defensin; lysozyme; macrophage; neutrophil; oxygen radical

Most bacteria are killed during phagocytosis by oxygen radicals, which are formed during the respiratory burst when phagosomes and lysosomes merge. When oxygen radical production is excessive, tissue damage occurs. Lysozymes, defensins, and bacteriocidal permeability-increasing (BPI) protein also destroy bacteria and other organisms; their actions do not depend on the generation of oxygen radicals.

induced phagocytosis

Phagocytosis that is stimulated by the presence of opsonins such as antibodies.

spontaneous phagocytosis

Phagocytosis that occurs in the absence of opsonins.

phagocytosis

The envelopment and destruction of bacteria or other foreign bodies by PHAGOCYTES.

phagocytosis

the ingestion of materials (subcellular particles, cells) from the outside of a cell into its interior, forming a cytoplasmic vacuole.

Phagocytosis

A process by which a white blood cell envelopes and digests debris and microorganisms to remove them from the blood.

phagocytosis

process of ingestion and digestion of particles, foreign material, necrotic or degenerate tissue or bacteria by phagocytic cells, e.g. macrophages

phagocytosis 

The process of ingestion of solid substances (e.g. cells, bacteria, parts of necrosed tissue) by cells and transported to a site within the cell where it is broken down by lysosomal enzymes.

phag·o·cy·to·sis

(fāg'ō-sī-tō'sis)
Process of ingestion and digestion by cells of solid substances.
[phagocyte + G. -osis, condition]

phagocytosis (fag´əsītō´sis),

n the engulfing of microorganisms, cells, and other substances by phagocytes. See also phagocyte.

phagocytosis

the engulfing of microorganisms or other cells and foreign particles by phagocytes.
Enlarge picture
Phagocytosis. By permission from Roitt I, Brostoff J, Male D, Immunology, Mosby, 2001
References in periodicals archive ?
Effect of probiotic treatment in broiler chicks on intestinal macrophage numbers and phagocytosis of Salmonella Enteritidis by abdominal exudate cells.
2004) proposed to define the "unhealthy" immune response profile of unfed oysters as displaying low phagocytosis and a high respiratory burst.
the acute phase reactant, C-reactive protein, which binds to the C-polysaccharide of many bacteria, promoting phagocytosis
Because several aspects of innate immunity are altered in patients with diabetes, namely, depressed polymorphonuclear leukocyte function and altered leukocyte adherence, chemotaxis, and phagocytosis (Delamaire et al.
Receptor- mediated endocytosis and phagocytosis by rainbow trout head kidney sinusoidal cells.
If the particle concentration is too high to be removed by the lymphatic system, the macrophages in the vicinity attempt to engulf the wear particles by phagocytosis.
The smear was observed under oil immersion objective (X100) of a light microscope (Olympus, Japan) and the percentage phagocytosis was determined by counting 200-300 stained PMN per slide.
It is believed that the substance helenalin found in the flower heads of the plant stimulates phagocytosis, the process by which cells clear out waste and repair tissue damage.
The impairment of phagocytosis leads to severe infections, as can be seen in patients with primary and secondary immunodeficiencies (1-6).
Lyn seems to be a very potent signaling mediator in both epithelial and macrophage cell types and orchestrates many downstream pathways that regulate cytoskeletal changes for effective phagocytosis and increased expression of pro-inflammatory cytokines.
There are several possible explanations for this negative effect of antioxidants on mortality, one of which is that by eliminating (or reducing) free radicals we are interfering with some of the body's essential defence mechanisms such as apoptosis, phagocytosis and detoxification which depend on reactive oxygen species.
The pathophysiology of vascular damage in maternal decidual vasculopathy is unknown, but the 2 key findings in the involved vessels in this lesion are well described: (1) atherosis appears to be histiocytic phagocytosis of damaged endothelial cells of the spiral arteries, and (2) the dense pink fibrinoid necrosis may be some amalgam of the coagulation cascade proteins and intermediate filaments.