phaeochromocytoma


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Related to phaeochromocytoma: adrenal gland

phe·o·chro·mo·cy·to·ma

(fē'ō-krō'mō-sī-tō'mă)
A functional chromaffinoma, usually benign, derived from adrenal medullary tissue cells and characterized by the secretion of catecholamines, resulting in hypertension, which may be paroxysmal and associated with attacks of palpitation, headache, nausea, dyspnea, anxiety, pallor, and profuse sweating.
See also: paraganglioma
Synonym(s): phaeochromocytoma.
[G. pheo + G. chrōm, color; -oma - tumor]

phaeochromocytoma

A rare ADRENALINE-secreting tumour of the inner part of an ADRENAL gland or occurring in similar tissue elsewhere in the body. The resulting excessive levels of adrenaline in the blood cause a severe and sometimes dangerous rise in the blood pressure as well as other distressing effects such as emotional upset, a rapid pulse, palpitations, nausea, vomiting and headache. Treatment is by surgical removal of the tumours.

phaeochromocytoma

benign, catecholamine (adrenaline and noradrenaline)-secreting tumour; causes severe paroxysmal hypertension

phe·o·chro·mo·cy·to·ma

(fē'ō-krō'mō-sī-tō'mă) [MIM*171300]
A functional chromaffinoma characterized by secretion of catecholamines, resulting in hypertension.
Synonym(s): phaeochromocytoma.
[G. pheo + G. chrōm, color; -oma - tumor]

phaeochromocytoma

see pheochromocytoma.

pheochromocytoma, phaeochromocytoma

a small chromaffin cell tumor, usually located in the adrenal medulla but occasionally occurring in chromaffin tissue of the sympathetic paraganglia. It occurs most often in dogs and cattle; in bulls it develops concurrently with C-cell tumors of the thyroid gland. Functional tumors secrete catecholamines, causing arteriolar sclerosis and medial hyperplasia and clinical signs of hypertension: tachycardia, edema and cardiac hypertrophy.
References in periodicals archive ?
Adrenal carcinomas, phaeochromocytomas and clear cell renal cell carcinoma metastases can contain variable amounts of fat and may demonstrate signal loss on OP images.
Whereas 10-26% of phaeochromocytomas are malignant, intra-abdominal extra-adrenal paragangliomas have higher malignant potential (up to 50%), with spread possible to lymph nodes, liver and lung.
5 mEq/L) 2 Increased plasma aldosterone (>15 ng/dL) Phaeochromocytoma 4 Elevated 24-hour urine catecholamines Hyperandrogenism 3 Elevated DHEA/17 ketosteroids Table 3.
A phaeochromocytoma is a rare neuro-endocrine tumour of the paraganglionic chromaffin cells affecting 2-8 persons per million per year.
I-131-meta-iodobenzylguanidine (MIBG) has been shown to be effective in chromaffin tumours (neuroblastoma, phaeochromocytoma, and paraganglioma) as well as for carcinoid and medullary thyroid carcinoma.
MEN II (bilateral phaeochromocytoma and thyroid carcinoma) was not diagnosed in a patient with suspected acute myocarditis and cardiovascular failure (no correct test was performed).
Contraindications: Hypersensitivity to any ingredient, heart disease, hepatic or severe renal impairment, hypertension, hyperthyroidism, diabetes, phaeochromocytoma, closed angle glaucoma or use with other sympathomimetic decongestants.
2) Acquired LQTS may be drug induced, (3,5) or due to electrolyte abnormalities such as acute hypokalemia or chronic hypokalemia, hypocalcemia, hypomagnesemia or medical conditions such as complete atrioventricular block, myocarditis, cardiac failure, encephalitis, stroke, head trauma, subarachnoid hemorrhage, anorexia nervosa, hyperparathyroidism, hypothyroidism and phaeochromocytoma.
It can be used in large doses for the short term control of hypertension in patients with phaeochromocytoma or in the treatment of hypertensive crisis following the abrupt withdrawal of clonidine.
Multiple endocrine neoplasia type 2 (MEN2) syndromes are autosomally dominant clinical associations characterised by a number of tumours, including medullary thyroid carcinoma (MTC), phaeochromocytoma, thyroid C-cell hyperplasia (CCH), parathyroid tumours (MEN2A) and ganglioneuroma of the gastrointestinal tract (MEN2B).
Phaeochromocytoma was finally excluded due to the presence of a basophilic cytoplasm and the obvious absence of S100 positive sustentacular cells.
Bilateral phaeochromocytoma in pregnancy: anaesthetic management of combined caesarean section and tumor removal.