persistent foramen ovale


Also found in: Acronyms.

persistent foramen ovale

Failure of the hole in the wall between the two upper chambers of the heart to close fully at birth. This opening is necessary during fetal life so that blood can bypass the lungs, but changes in pressure normally cause it to close after birth. In some cases a small opening remains, but this is usually harmless.
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References in periodicals archive ?
Prothrombin G20210A mutation, but not factor V Leiden, is a risk factor in patients with persistent foramen ovale and otherwise unexplained cerebral ischemia.
Morrison, Inheritance of persistent foramen ovale and atrial septal defects and the relation to familial migraine with aura.
A persistent Foramen ovale (PFO) can be observed in about 30% of all adults and 40% of children.

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