peroxisome


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peroxisome

 [pĕ-roks´ĭ-sōm]
a microbody found in vertebrate animal cells, especially kidney and liver cells, that contains urate oxidase, amino acid oxidase, catalase, and other enzymes.

pe·rox·i·some

(pĕ-rok'si-sōm),
A membrane-bound organelle occurring in many eukaryotic cells that often has an electron-dense crystalline inclusion containing catalase, urate oxidase, and other oxidative enzymes relating to the formation and degradation of H2O2; thought to be important in detoxifying various molecules and in catalyzing the breakdown of fatty acids to acetyl-CoA; an absence of peroxisomes is found in patients with Zellweger syndrome.
[peroxide + G. sōma, body]

peroxisome

/per·ox·i·some/ (-ok´sĭ-sōm)
1. any of the microbodies present in vertebrate animal cells, especially liver and kidney cells, which are rich in the enzymes peroxidase, catalase, d-amino acid oxidase, and, to a lesser extent, urate oxidase.
2. microbody (1).

peroxisome

(pə-rŏk′sĭ-sōm′)
n.
A cell organelle containing a large number of enzymes, including catalase and oxidase, that break down long-chain fatty acids and other organic molecules. The hydrogen peroxide produced by these reactions is also broken down within the peroxisome.

per·ox′i·som′al (-sō′məl) adj.

peroxisome

[pər·ok′si·sōm]
any of the microbodies present in vertebrate animal cells, especially liver and kidney cells, that are rich in the enzymes peroxidase, catalase, d-amino acid oxidase, and, to a lesser extent, urate oxidase. Their functions are not fully understood, but they participate in metabolic oxidations involving hydrogen peroxide, purine metabolism, cellular lipid metabolism, and gluconeogenesis. See microbody.

pe·rox·i·some

(pĕr-ok'si-sōm)
A membrane-bound organelle occurring in nearly all eukaryotic cells that often contains oxidative enzymes relating to the formation and degradation of H2O2.
Synonym(s): microbody.
[peroxide + G. sōma, body]

peroxisome

an organelle of EUKARYOTE cells which is surrounded by a single unit membrane. Peroxisomes contain PEROXIDASES and may be concerned with the production of molecular oxygen from the breakdown of hydrogen peroxide. They are located near MITOCHONDRIA and plant CHLOROPLASTS, and appear to be involved in CELLULAR RESPIRATION.

peroxisome

a membrane-bound body found in vertebrate animal cells, especially kidney and liver cells, that contains urate oxidase, amino acid oxidase, catalase and other enzymes.
References in periodicals archive ?
Differential expression of peroxisome proliferator-activated receptors alpha and gamma gene in various chicken tissues.
Distribution of peroxisome proliferator-activated receptors (PPARs) in human skeletal muscle and adipose tissue: relation to insulin action.
Peroxisome proliferators activated receptor-[gamma], a key component in regulation of growth and progression of mammary cancer, is expressed in normal as well as in malignant mammary epithelial cells and its activation by ligands induces cellular differentiation (16,17).
Fatty acids elicit several physiological effects through alteration of the activity and/or synthesis of peroxisome proliferator-activated receptors (PPAR).
The drugs, including Actos and Avandia, work by activating proteins called peroxisome proliferators-activated receptors, or PPARs.
There are also detailed notes on testing the likely effect of plastics monomers and additives in digestive fluids, assessing accumulation of trace elements in consumers and on peroxisome proliferation studies, among other procedures.
The transcription factor Peroxisome Proliferator Activated Receptor [gamma] has been shown to he involved in a variety of physiological processes including adipocyte differentiation, fat storage, inflammatory response, and insulin sensitization in liver and muscle tissue.
Dubois M, Pattou F, Kerr-Conte J, et al: Expression of peroxisome proliferator-activated receptor gamma (PPARagamma) in normal human pancreatic islet cells.
with overexpresssion of HER2/neu or overexpression of epidermal growth factor receptor, are treated with strongly binding PPAR gamma ligands, and patients affected with cancer associated with overexpression of at least one member of the class I family of receptor tyrosine kinases selected from the group consisting of HER-2/neu and epidermal growth factor rector, comprising administering to said patient a therapeutically effective amount of a ligand of peroxisome proliferator-activated receptor gamma (PPAR gamma) which has a pKi of at least 4.
2013) reported that 13 tag single nucleotide polymorphisms in the peroxisome proliferator-activated receptor (PPAR) signaling pathway are associated with porcine meat quality traits.
Peroxisome proliferator-activated receptor alpha (PPARalpha) is known to control fat metabolism in the liver.

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