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permissive hypercapnia

   Also found in: Wikipedia 0.01 sec.
permissive hypercapnia,
ventilation that allows PaCO2 to rise slowly over time as the pH becomes normalized. The goal is to reduce tidal volume and rate while preventing volutrauma during mechanical ventilation. Patients may need to be sedated during this.

permissive hypercapnia
Critical care An approach to management of acute respiratory failure in which the tidal volume–VT is lower–5-8 mL/kg than that conventionally used–10-15 mL/kg, the arterial Pco2 is allowed to rise above the 'normal' of 40 mm Hg, and no attempts are made to compensate for subsequent changes in blood pH–respiratory acidosis, the deleterious effects of which may have been overestimated


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Mathematical models easily demonstrated the critical importance of minute ventilation in driving dynamic hyperinflation, and gave a potent rationale for pursuing a strategy of permissive hypercapnia in the ventilatory support of severe airflow obstruction--long before its use in ARDS.
Relatively recent mechanical ventilation strategies such as permissive hypercapnia and the use of low tidal volumes have somewhat improved the prognosis.
 
 
 
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