However, no hemorrhage and necrosis were found in liver samples of rabbits pre-treated with IP and adenosine, with vacuolar and granular degeneration in the perivenular
zones and mild to moderate inflammation being the prevailing alterations.
There were perilymphatic and perivenular
hepatocytes), then progressing to mid-lobular hepatocytes, and finally to the hepatocytes that surround the hepatic portal vein (i.
3) Pathologic changes in biopsied or explanted livers of patients with Budd-Chiari characteristically include perivenular
necrosis, sinusoidal dilation, and occasionally formation of macronodules resembling focal nodular hyperplasia.
4] Next, mAST is found in perivenular
area in the liver around the central vein.
Autopsy studies reveal that in NB disease, low-grade chronic lymphocytic meningo-encephalitis with widespread perivenular
neutrophilic or lymphocytic and plasmocytic cuffing, multifocal necrotic foci are observed.
MS lesions are often located in a perivenular
Alcoholic hepatitis is usually associated with proliferation of sinusoidal stellate cells and portal tract fibroblast, giving rise to sinusoidal and perivenular
There were corresponding morphologic changes: at 36 months, 2 of 6 animals fed alcohol had cirrhosis and 2 septal fibrosis, with perivenular
fibrosis in 2, whereas with alcohol + silymarin, there was only 1 cirrhosis and 1 septal fibrosis, with perivenular
fibrosis in 2, and virtually no lesions in the remaining 2.
2007) who postulated that the liver steatosis states in the central perivenular
area but it may involve the total surface of the lobule.
Liver section of atherodiet fed animals shows marked perivenular
inflammatory fatty changes, which are comparatively mild in chloroform extract (Figure 3).
Los estadios mas tempranos de fibrosis en HGNA se observan en los espacios perisinusoidales con localizacion preferencial en la zona perivenular
o zona 3.