Our patient was a 32-year-old male, non-hypertensive, non-diabetic, who fulfilled five major criteria (facial angiofibromas, periungual
fibromas, ash leaf spots, cortical dysplasia, subependymal nodules (SEN), renal angiomyolipomas) of tuberous sclerosis complex (TSC) as per diagnostic criteria of the 2012 International Tuberous Sclerosis Complex Consensus Conference (Box 1).
Using a periungual
puncture site, pain was not referred by any subject, although a bothersome sensation was noted by some.
3) Characteristic skin manifestations include heliotrope rash, periungual
telangiectasia, edema, and facial erythema, with the hallmark being Gottron's papules--scaling, erythematous eruptions over the knuckles and other extensor surfaces.
In patients with tuberous sclerosis complex, hypomelanotic macules and fibrous plaques occur earlier compared to typical facial angiofibromas or periungual
fibroma (Koenen tumors) as isolated sign of tuberous sclerosis complex with tuberous sclerosis complex 1 germline mutation.
Physical examination showed less induration of the skin, resolution of the periungual
erythema, and increased range of movement of the fingers.
and subungual warts caused by high-risk HPV subtypes pose a risk for malignant transformation .
Onychomycosis is defined as a fungal infection of the nail unit (Figure 1): the nail plate, nail bed, and periungual
Subaguda: descamacion periungual
en los dedos de las manos, en los dedos de los pies en las semanas 2 y 3 de la enfermedad
Siddetli tutulumda, ozellikle periungual
granulasyon dokusuna yonelik cerrahi girisimler de yapilabilir (20).
Features suggesting malignancy include older age, male gender, rapid onset of skin or muscle symptoms, skin necrosis, and periungual
These lesions are painless, slow growing, present 3 months to 30 years before resection, and involve the subungual or periungual
region of the fingers and toes.