Disseminated nodular granulomatous perifolliculitis
Familial perifolliculitis capitis abscedens et suffodiens in two brothers successfully treated with isotretinoin.
Successful treatment of perifolliculitis capitis abscedens et suffodiens with combined isotretinoin and dapsone.
Of 8 birds, Staphylococcus species was isolated from only 1 sample, a feather that was associated with mononuclear perifolliculitis
Observation of parasitic skin diseases demonstrated a high frequency of canine demodicosis, diagnosed by the presence of perifolliculitis
, mural folliculitis and follicle rupture, besides the presence of the parasite, in agreement with literature reports (1).
HS is characterized by perifolliculitis
which may destroy the pilosebaceous unit and in healing stages, by fibrosis6 and so was excluded in our case.
The histopathology of samples taken from the head and scalp reported occlusion folliculitis with mixed inflammatory infiltrate predominantly polymorphonuclear with destruction of the epidermal basal layer, stratum corneum spongiosis, exocytosis, and formation of intraepidermal abscesses; the inflammatory infiltrate compromised the follicular epithelium and the adjacent adnexal structures, findings compatible with acne conglobata and perifolliculitis capitis abscedens et suffodiens (Figure 1).
Perifolliculitis capitis abscedens et suffodiens is a rare, chronic, progressive, and inflammatory disease of the scalp, which almost exclusively affects Afro- descendant males (80%) between 18 and 40 years of age.
1) Sarcoidosis 6 0 Systemic mast cell disease 1 0 Toxoplasmosis 1 0 Lymph nodes with metastatic tumors 27 0 Carcinoma 25 0 Melanoma 2 0 Other inflammatory tissues 7 0 Chronic sialadenitis 1 0 Follicular bronchiolitis 1 0 Hemophagocytic syndrome, spleen 1 0 Helicobacter pylori-associated gastritis 1 0 Hemochromatosis, liver 1 0 Hyperplasia and chronic perifolliculitis
, skin 1 0 Interstitial pneumonitis 1 0 Other neoplastic tissues 13 0 Mixed mullerian tumor 1 0 Neurofibroma 1 0 Sarcoma 4 0 Schwannoma 2 0 Thymoma 5 0 * MCPyV, Merkel cell polyomavirus.
A biopsy was taken of the occipital scalp lesion, and histopathology found that it was consistent with acute perifolliculitis
Compared with the baseline biopsy, the last biopsy showed a lower percentage of follicles with perifolliculitis