Indirect ultrasonographic lymphography with perflubron
The PFC liquids used to support pulmonary gas exchange are a type of synthetic liquid fluorinated hydrocarbon (hydrocarbons with the hydrogen replaced by fluorine, and for perflubron
where a bromine atom is added as well) with high solubility for oxygen and carbon dioxide.
A new oxygen-bearing lubricant, called perflubron
, has been tested on 13 premature infants with severe surfactant deficiency.
Thanks to this oxygen-bearing lubricant, called perflubron
, the baby was one of eight to survive a crisis known as surfactant deficiency.
Shepherd and Steinke (1) reported that perflubron
emulsion, a potential blood substitute soon to be in clinical use, interferes with measurements by several CO-oximeters.
emulsion (Oxygent [TM]) is now in advanced clinical trials as a non-hemoglobin, oxygen-carrying blood substitute and is expected to be in clinical use soon.
A PFC product currently in clinical trials is Perflubron
from Alliance Pharmaceuticals.
X91, the other a PFC-based oxygen carrier, Perflubron
emulsion from Alliance Pharmaceutical Corp.