peptide antibiotic

peptide antibiotic

antibiotic composed of peptides; the antibacterial action is based on the physical disruption of cell membranes.

pep·tide an·ti·bi·ot·ic

(pep'tīd an'ti-bī-ot'ik)
An antibiotic composed of peptides; its antibacterial action is based on the physical disruption of cellular membranes.
References in periodicals archive ?
Some rrs mutations also confer resistance to the cyclic peptide antibiotic CAP .
Engineered biosynthesis of the peptide antibiotic bacitracin in the surrogate host Bacillus subtilis.
The trial, developed in consultation with the US Food & Drug Administration (FDA), was designed to substantiate the safety of MBI 226, a novel peptide antibiotic for the prevention of central venous catheter-related bloodstream infection.
Demegen currently has a number of pre-clinical programs underway to develop peptide antibiotic products.
Other protein therapeutics covers proteins such as cytokines, fusion proteins, peptide antibiotics, peptide hormones, and blood factors.
These endogenous peptide antibiotics have broad-spectrum antimicrobial activity and can also modulate the composition of gut microbiota.
Currently, there is a great interest in peptide antibiotics, especially the cationic peptides, which help in disruption of cell membrane, therefore, peptide antibiotics may not face the rapid emergence of resistance (4).
Some cell enzymes and oligomers, they say, as are some peptide antibiotics, genes, hormones, and many other important bioactive substances.
Several peptide antibiotics (also known as antimicrobial peptides or natural antibiotics), in particular defensins, have also been shown to display in vitro antiviral activity (Bastian and Schafer, 2001; Lehrer, 2004; Matanic and Castilla, 2004).
The proteins, bacteriocins, are bacterially produced peptide antibiotics with the ability to kill a limited range of bacteria, usually--but not always--those that are closely related to the producer bacterium.
Peptide antibiotics may also be effective against other types of pathogens besides bacteria - perhaps even against viruses.