Some rrs mutations also confer resistance to the cyclic peptide antibiotic
Subtilin is a small peptide antibiotic
of 32 amino acids produced by B.
Engineered biosynthesis of the peptide antibiotic
bacitracin in the surrogate host Bacillus subtilis.
The trial, developed in consultation with the US Food & Drug Administration (FDA), was designed to substantiate the safety of MBI 226, a novel peptide antibiotic
for the prevention of central venous catheter-related bloodstream infection.
Demegen currently has a number of pre-clinical programs underway to develop peptide antibiotic
Other protein therapeutics covers proteins such as cytokines, fusion proteins, peptide antibiotics
, peptide hormones, and blood factors.
These endogenous peptide antibiotics
have broad-spectrum antimicrobial activity and can also modulate the composition of gut microbiota.
Currently, there is a great interest in peptide antibiotics
, especially the cationic peptides, which help in disruption of cell membrane, therefore, peptide antibiotics
may not face the rapid emergence of resistance (4).
Some cell enzymes and oligomers, they say, as are some peptide antibiotics
, genes, hormones, and many other important bioactive substances.
Several peptide antibiotics
(also known as antimicrobial peptides or natural antibiotics), in particular defensins, have also been shown to display in vitro antiviral activity (Bastian and Schafer, 2001; Lehrer, 2004; Matanic and Castilla, 2004).
The proteins, bacteriocins, are bacterially produced peptide antibiotics
with the ability to kill a limited range of bacteria, usually--but not always--those that are closely related to the producer bacterium.
may also be effective against other types of pathogens besides bacteria - perhaps even against viruses.