pepsinogen


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Related to pepsinogen: trypsinogen

pepsinogen

 [pep-sin´o-jen]
a zymogen secreted by the chief cells of the gastric glands and converted into pepsin in the presence of gastric acid or of pepsin itself.

pep·sin·o·gen

(pep-sin'ō-jen), [MIM*169700]
A proenzyme or zymogen formed and secreted by the chief cells of the gastric mucosa; the acidity of the gastric juice and pepsin itself remove 44 amino acyl residues from pepsinogen to form active pepsin.
Synonym(s): propepsin
[pepsin + G. -gen, producing]

pepsinogen

/pep·sin·o·gen/ (pep-sin´ah-jin) a zymogen secreted by the chief cells of the gastric glands and converted into pepsin in the presence of gastric acid or of pepsin itself.

pepsinogen

(pĕp-sĭn′ə-jən)
n.
The inactive precursor to pepsin, formed in cells of the mucous membrane of the stomach and converted to pepsin by autocatalysis in the presence of hydrochloric acid.

pepsinogen

[pəpsin′əjən]
Etymology: Gk, pepsis + genein, to produce
a zymogenic substance secreted by pyloric and gastric chief cells. It is converted to the enzyme pepsin in an acidic environment, as in the presence of hydrochloric acid produced in the stomach.

pep·sin·o·gen

(pep-sin'ŏ-jen)
A proenzyme formed and secreted by the chief cells of the gastric mucosa; the acidity of the gastric juice and pepsin itself remove 42 amino acid residues from pepsinogen to form active pepsin.
Synonym(s): propepsin.
[pepsin + G. -gen, producing]

pepsinogen

A biochemically inert substance produced by the cells of the stomach lining (gastric mucosa) that is converted to PEPSIN by the action of hydrochloric acid.

pepsinogen

a precursor of PEPSIN in the vertebrate stomach which, in the presence of hydrochloric acid (also secreted by the OXYNTIC CELLS in the stomach wall), gives rise to more active pepsin, which itself activates pepsinogen. The reaction is thus auto catalytic.

pepsinogen

a zymogen secreted by the chief cells of the gastric glands and converted into pepsin in the presence of gastric acid or of pepsin itself.

plasma pepsinogen
high levels are indicative of extensive mucosal damage in the abomasum, as in ostertagiasis in ruminants.
References in periodicals archive ?
Effect of carrier protein in pepsinogen standard preparation.
A single Asp-N-mediated cleavage of pepsinogen affords the targeted peptide.
In the current case, the target analyte pepsinogen is not typically present in detectable quantities in saliva, thus analyte-free saliva matrix is relatively easy to obtain.
We tested dilution linearity using a 744 pmol/L (30 [micro]g/L) pepsinogen spike in a human saliva pool after 2-, 5-, and 10-fold dilution with 20 mmol/L ammonium bicarbonate, pH 7.
Pepsinogen spiked at 198 pmol/L in a human saliva pool was found to be stable to 1, 2, and 3 freeze/ thaw cycles.
We evaluated benchtop stability of pepsinogen spiked at 198 pmol/L (8.
To check if pepsinogen C interacts with components of the biological fluids leading to its inactivation or complexation, we prepared pepsinogen C radioactively labeled with [sup.
A BSA matrix contains two peaks of radioactivity, one for pepsinogen C (around fraction 38, molecular mass ~35 kDa) and one for free [sup.
To obtain preliminary information on the presence of pepsinogen C in biological fluids, we analyzed various clinical samples as shown in Table 1.
The gene for pepsinogen C has been cloned and sequenced [30].
Pepsinogen C is reportedly present at high concentrations in breast secretions and in breast tumor extracts.
Among these molecules are pepsinogen C, PSA, apolipoprotein D, and Zn-[[alpha].