pentoxifylline

pentoxifylline /pen·tox·i·fyl·line/ (pen?tok-sif´ah-lin) a xanthine derivative that reduces blood viscosity; used for the symptomatic relief of intermittent claudication.

---

pen·tox·if·yl·line (pntk-sf-ln, -ln, pn-tks-fln, -n)

n.

A bitter-tasting compound that decreases blood viscosity and improves blood flow, used in the treatment of intermittent claudication.

---

pentoxifylline (pen´toksif´lēn´),

n brand name: Trental;
drug class: hemorrheologic agent;
action: decreased blood viscosity, stimulates prostacyclin formation, increases blood flow by increasing flexibility of red blood cells (RBCs), decreased RBC hyperaggregation, reduces platelet aggregation, decreases fibrinogen concentration;
uses: intermittent claudication related to chronic occlusive vascular disease.

---

pentoxifylline

a methylxanthine derivative that causes an increase in microvascular blood flow and has an immunomodulating effect by suppression of proinflammatory cytokines. Used in the treatment of some canine skin diseases, especially vasculitis and dermatomyositis.