pentosan polysulfate


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pentosan polysulfate

Oncology An angiogenesis inhibitor that may block effects of growth factors on endothelial cells and protect the GI tract against RT Urology A drug used to relieve bladder pain due to interstitial cystitis. See Angiogenesis inhibitor.

pentosan polysulfate

a chondroprotective drug used in the treatment of osteoarthritis in dog and cats.
References in periodicals archive ?
Paradigm Biopharmaceuticals (ASX: PAR) has successfully dosed the first patient in the Phase 2b clinical trial for pentosan polysulfate sodium (PPS) as a treatment for knee osteoarthritis, Proactive Investors reported on Monday.
The sole medication approved by the Food and Drug Administration for IC is pentosan polysulfate sodium (Elmiron), and it should be reserved for the minority of patients who don't experience significant improvement after giving the diet a reasonable shot, Dr.
I am not a fan of pentosan polysulfate sodium (Elmiron) as it is a very expensive medication that has minimal benefit for the majority of patients.
Under the Imprimis Cares program, Imprimis offers a customizable pentosan polysulfate sodium delayed release (PPS-DR) compounded medication as an alternative to Elmiron for the treatment of symptoms associated with interstitial cystitis, at a cost savings of 88 percent.
39,40) However, in a phase 4 dosing study for pentosan polysulfate (PPS), an epithelial-directed therapy, no difference in response to PPS was observed.
Randomized, doubleblind, dose-ranging study of pentosan polysulfate sodium for interstitial cystitis.
Introduction of sodium pentosan polysulfate and avoidance of urethral catheterisation: Improved outcomes in children with haemorrhagic cystitis post stem cell transplant/chemotherapy.
Antileukemic activity of viva natural, a dietary seaweed extract, on Rausher murine leukemia in comparison with anti-HIV agents, azidothymidine dextran sulfate and pentosan polysulfate.
Use pentosan polysulfate with caution; although the drug is approved for the treatment of IC, recent studies indicate it has little benefit.
They found that treating hypertensive rats with the broad-acting anti-inflammatory drug pentosan polysulfate preserves the kidney's ability to regulate pressure placed on tiny filters called glomeruli.
Oral medications used for IC/PBS include pentosan polysulfate sodium, amitriptyline, and hydroxyzine.
Potential use of pentosan polysulfate for the treatment of equine joint disease.