pentamidine


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Related to pentamidine: Pentamidine isethionate

pentamidine

 [pen-tam´ĭ-dēn]
an antiinfective used as the isethionate salt, administered intravenously or intramuscularly in treatment of early African trypanosomiasis and leishmaniasis, and intravenously, intramuscularly, or by oral inhalation in treatment and prophylaxis of Pneumocystis cariniipneumonia.

pentamidine

/pen·tam·i·dine/ (pen-tam´ĭ-dēn) an antiinfective used as the isethionate salt in the treatment of pneumonia, leishmaniasis, and early African trypanosomiasis.

pentamidine

A drug used in the treatment of PNEUMOCYSTIS CARINII PNEUMONIA and TRYPANOSOMIASIS. It was the exceptional demand for pentamidine in 1981that heralded the onset of the AIDS pandemic. The drug is on the WHO official list. A brand name is Pentacarinat.
References in periodicals archive ?
Successful treatment of Colombian cutaneous leishmaniasis with four infections of pentamidine.
At that time, it was not yet known that nebulised pentamidine was both a cytotoxic drug and one that often induced coughing and therefore should be administered in a negative-pressure environment, but it was prescribed to the majority of our patients, and we administered it in groups of three to six patients.
The drug of choice for treating the hemolymphatic stage of Gambian sleeping sickness is pentamidine isethionate as it has a cure rate of 93-98%.
Pentamidine initially used as a second-line drug, acquired resistance (25%) even with prolonged dosage (17).
Extrapulmonary infection becomes more evident when prophylaxis is focused on the respiratory tract, and this may explain the correlation with the use of aerosolised prophylactic pentamidine.
spironolactone, triamterene, amiloride, ACE inhibitors, ARBs, trimethoprim, pentamidine, cyclosporine, tacrolimus, heparin)
Targeted at pneumocystis carinii pneumonia (PCP), the largest cause of death in AIDS patients, pentamidine was approved in 1984.
The compound called pentamidine carries approval of the U.
If children are unable to tolerate co-trimoxazole, for whatever reason, nebulised pentamidine is given as a prophylactic agent monthly in the PTC.
Although liposomal amphotericin B is the most often advised treatment for VL currently, our results with meglumine antimonate (MA; glucantime), which began with a dose of 20 mg/kg/day for 3 days, was increased to 30 mg/kg/day for 3 days and/or then increased to 60 mg/kg per day for 2 weeks, for a total of 20 days) followed by pentamidine isethionate (PI) every other day for a total 15 doses (2.