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pentagastrin test

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pentagastrin test,
(for gastric function) a test comparing basal acid output with a peak acid output. After the patient fasts overnight, a basal acid output and its pH are obtained for secretion of stomach acid. Then pentagastrin is administered into the stomach through a nasogastric tube and maximal acid output and peak acid output values are obtained. Also called pentagastrin stimulation test.

pentagastrin test
GI disease A test in which gastric acid secretion–GAS is stimulated with pentagastrin, a synthetic analogue of gastrin; GAS ↑ 10 mins post-injection, peaks at 20-30 mins, and lasts for < 2 hrs; the peaks in GAS are similar to those evoked by histamine–once used for the same purpose, with fewer adverse effects; PT is used to exclude achlorhydria in Pts with gastric ulcers


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