penicillinase /pen·i·cil·lin·ase/ (pen″ĭ-sil´ĭ-nās) a β-lactamase preferentially cleaving penicillin.
penicillinase
pen·i·cil·li·nase (p n  -sl -n s)n. See beta-lactamase. |
penicillinase
[pen′əsil′ənās]
an enzyme elaborated by certain bacteria, including many strains of staphylococci, that inactivates penicillin and thereby promotes resistance to the antibiotic. A purified preparation of penicillinase, derived from cultures of saprophytic spore-forming Bacillus cereus, is used in the treatment of adverse reactions to penicillin. Also called beta-lactamase.
penicillinase
an enzyme produced by bacteria that inactivates penicillin, thus increasing resistance to the antibiotic; a purified form from Bacillus cereus is used in the treatment of reactions to penicillin.
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