pemphigus vulgaris

pemphigus /pem·phi·gus/ (-gus)

1. a distinctive group of diseases marked by successive crops of bullae.

2. pemphigus vulgaris.

---

benign familial pemphigus  a hereditary, recurrent vesiculobullous dermatitis, usually involving the axillae, groin, and neck, with crops of lesions that regress over several weeks or months.

pemphigus erythemato´sus  a chronic form in which the lesions, limited to the face and chest, resemble those of disseminated lupus erythematosus.

pemphigus folia´ceus  a chronic, generalized, vesicular and scaling eruption somewhat resembling dermatitis herpetiformis or, later in its course, exfoliative dermatitis.

pemphigus ve´getans  a variant of pemphigus vulgaris in which the bullae are replaced by verrucoid hypertrophic vegetative masses.

pemphigus vulga´ris  a rare relapsing disease with suprabasal, intraepidermal bullae of the skin and mucous membranes; invariably fatal if untreated.

---

pemphigus vul·gar·is (vl-gârs)

n.

Pemphigus occurring in middle age, in which cutaneous flaccid acantholytic suprabasal bullae and oral mucosal erosions are first localized but become generalized after a few months, forming blisters that break easily and are slow to heal.

---

pemphigus vulgaris

Etymology: Gk, pemphix, bubble; L, vulgus, common

a chronic, progressive autoimmune disease that is often fatal, characterized by the formation of bullae on otherwise normal oral mucosal membrane. Also called pemphigus chronicus.

---

pemphigus

[Gr.] pemphix (blister); a group of immune-mediated diseases of the skin and mucous membranes characterized by vesicles, bullae, erosions and ulcerations; occurs in dogs, cats and horses.

---

pemphigus erythematosus

a form with features of both pemphigus foliaceus and lupus erythematosus; occurs in dogs and cats. There are erythematous, pustular lesions, mainly on the nose, periorbital skin and pinnae, and hypopigmentation of the planum nasale.

pemphigus foliaceus

a generalized, exfoliative, scaling disease sometimes with the formation of heavy crusts, marked hyperkeratosis of footpads, and involvement of the nail beds that may lead to loss of the nails. Occurs in dogs, cats, horses and goats.

pemphigus vegetans

a benign variant of pemphigus vulgaris, occurring only rarely in animals, in which the bullae are replaced by verrucoid hypertrophic vegetative masses.

pemphigus vulgaris

consists of shallow ulcerations with a generalized distribution and frequently involving the mucocutaneous junctions and oral mucosa.

---

pemphigus vulgaris

Dermatology An autoimmune disorder characterized by acantholysis and blistering of mucocutaneous surface primarily in older people Etiology Immune response to penicillamine and captopril; > 95% of Pts have specific HLA antigens; ±50% of Pts begin with blisters in the mouth, followed by skin