paroxysmal nocturnal hemoglobinemia

paroxysmal nocturnal hemoglobinemia

an acquired hematopoietic stem cell disorder characterized by formation of defective platelets, granulocytes, erythrocytes, and possibly lymphocytes. The red blood cell abnormality causes complement-mediated intravascular lysis, which may be expressed in an irregular or even occult manner.

par·ox·ys·mal noc·tur·nal he·mo·glo·bi·ne·mi·a

(par'ok-siz'măl nok-tŭr'năl hē'mŏ-glō'bi-nē'mē-ă)
An acquired hematopoietic stem cell disorder characterized by formation of defective platelets, granulocytes, erythrocytes, and possibly lymphocytes. The erythrocyte abnormality causes complement-mediated intravascular lysis, which may be expressed in an irregular or even occult manner.
Mentioned in ?
Full browser ?